4-bromo-3-fluorobenzyl methanesulfonate

Base Information Edit

Chemical Name:4-bromo-3-fluorobenzyl methanesulfonate
CAS No.:1240286-88-7
Molecular Formula:C₈H₈BrFO₃S
Molecular Weight:283.118
Hs Code.:
Mol file:1240286-88-7.mol

Synonyms:4-bromo-3-fluorobenzyl methanesulfonate

Suppliers and Price of 4-bromo-3-fluorobenzyl methanesulfonate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-bromo-3-fluorobenzyl methanesulfonate Edit

Chemical Property:

Purity/Quality:: 95+% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-bromo-3-fluorobenzyl methanesulfonate

There total 5 articles about 4-bromo-3-fluorobenzyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 124-63-0
methanesulfonyl chloride

: 222978-01-0
4-bromo-3-fluorobenzyl alcohol

: 1240286-88-7
4-Bromo-3-fluorobenzyl methanesulfonate

Guidance literature:: With triethylamine; In dichloromethane; at -20 - 20 ℃;
DOI:10.1021/jm200866y

Reference yield:

: 849758-12-9
methyl 4-bromo-3-fluorobenzoate

: 1240286-88-7
4-Bromo-3-fluorobenzyl methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 48 h / 0 - 20 °C

2: triethylamine / dichloromethane / -20 - 20 °C

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jm200866y

Reference yield:

: 153556-42-4
4-bromo-3-fluorobenzoic acid

: 1240286-88-7
4-Bromo-3-fluorobenzyl methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / tetrahydrofuran; water; ethyl acetate

2: triethylamine; sodium hydrogencarbonate / water; dichloromethane

With sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; dichloromethane; water; ethyl acetate;