N-Methylhydroxylamine

Base Information

• Chemical Name: N-Methylhydroxylamine
• CAS No.: 593-77-1
• Molecular Formula: CH5 N O
• Molecular Weight: 47.0568
• UNII: V8920J3L6R
• DSSTox Substance ID: DTXSID10208035
• Nikkaji Number: J2.699I
• Wikipedia: N-Methylhydroxylamine
• Wikidata: Q18378717
• ChEMBL ID: CHEMBL144761
• Mol file: 593-77-1.mol

Synonyms:N-methylhydroxylamine;N-methylhydroxylamine hydrochloride

Chemical Property of N-Methylhydroxylamine

Chemical Property:

• Melting Point: 87.5°C
• Refractive Index: 1.4164 (estimate)
• Boiling Point: 55.67°C (rough estimate)
• PKA: 14.00±0.30(Predicted)
• PSA: 32.26000
• Density: 1.0003
• LogP: -0.01410
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 47.037113783
• Heavy Atom Count: 3
• Complexity: 4.8

Purity/Quality:

98%Min ^*data from raw suppliers

N-METHYLHYDROXYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNO

Technology Process of N-Methylhydroxylamine

There total 36 articles about N-Methylhydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloropicrin (76-06-2) → dichloroformoxime (1794-86-1) + N-Methylhydroxylamine (593-77-1) + trichloronitrosomethane (3711-49-7) + methylamine (74-89-5)

Guidance literature:

Bei der elektrolytischen Reduktion entstehen je nach den Bedingungen wechselnde Menge;

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + N-methyl-α-phenylnitrone (3376-23-6) → N-Methylhydroxylamine (593-77-1) + benzaldehyde (100-52-7)

Guidance literature:

Reference yield:

N-methyl-α-phenylnitrone (3376-23-6) + furan-2,3,5(4H)-trione pyridine (1:1) → N-Methylhydroxylamine (593-77-1) + benzaldehyde (100-52-7)

Guidance literature:

upstream raw materials:

acetaldehyde-(N-methyl oxime )

diethyl ether

2-chloro-2-nitrosopropane

dimethyl zinc(II)

Downstream raw materials:

N-methyl-N-(4-methoxybenzoyl)hydroxylamine

1-hydroxy-1-methyl-3-phenylthiourea

5-amino-2-methyl-4-phenyl-isoxazol-3-one

2,3-dimethyl-4-phenylazoisoxazol-5-one

Refernces

• 1、 Travalon, Silvana Azzolini,Brighente, Ines Maria Costa,Yunes, Rosendo Augusto. "Spontaneous dehydration mechanism of aromatic aldehyde reactions with hydroxyl and non-hydroxyl amines". . p. 685 - 692. Retrieved 2007/10/03.
• 2、 Brink, Klaus,Mattes, Rainer. "Hydrolysis of Di- and Trimesylhydroxylamines and their Methylated Derivatives". . p. 351 - 354. Retrieved 2007/10/02.