DESMOSTEROL ACETATE

Base Information

• Chemical Name: DESMOSTEROL ACETATE
• CAS No.: 2665-04-5
• Molecular Formula: C29H46O2
• Molecular Weight: 426.683
• Mol file: 2665-04-5.mol

Synonyms:5,24-CHOLESTADIEN-3BETA-OL 3-ACETATE;5,24-CHOLESTADIEN-3-BETA-OL ACETATE;24-DEHYDROCHOLESTEROL ACETATE;DESMOSTEROL ACETATE;5,24-Cholestadien-3β-ol acetate;Cholesta-5,24-dien-3β-ol 3-acetate;Cholesta-5,24-dien-3β-ol acetate

Chemical Property of DESMOSTEROL ACETATE

Chemical Property:

• PSA: 26.30000
• LogP: 7.87960

Purity/Quality:

99% ^*data from raw suppliers

DESMOSTEROL ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DESMOSTEROL ACETATE

There total 2 articles about DESMOSTEROL ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

25-hydroxychlolesterol (2140-46-7) → demosterol acetate (2665-04-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 19 h / Ambient temperature

2: pyridine, phosphoryl chloride / 0.5 h / Heating

With pyridine; trichlorophosphate;

DOI:10.1016/0039-128X(90)90010-9

Reference yield:

25-hydroxychlolesterol (2140-46-7) + acetic anhydride (108-24-7) → demosterol acetate (2665-04-5)

Guidance literature:

With acetic acid; for 2h; Heating;

DOI:10.1039/P19720002423

Reference yield: 86.2%

demosterol acetate (2665-04-5) → 25-hydroxychlolesterol (2140-46-7)

Guidance literature:

demosterol acetate; With LACTIC ACID; In 5,5-dimethyl-1,3-cyclohexadiene; at 55 ℃; for 5.5h;

With methanol; potassium hydroxide; In octane; at 25 ℃; for 3h;

upstream raw materials:

25-hydroxychlolesterol

acetic anhydride

Downstream raw materials:

demosterol

25-hydroxycholesteryl acetate

(5α,7α,24R)-7,24-dihydroxy-3-ketocholestane

(5α,24R)-24-benzoyloxy-7α-hydroxycholestan-3-one

Refernces

• 1、 Ikan,Markus,Goldschmidt. "Synthesis of steroidal cyclopropanes.". . p. 2423 - 2425. Retrieved 2007/10/17.