9β,10α-Pregna-4,6,8(14)-triene-3,20-dione

Base Information

• Chemical Name: 9β,10α-Pregna-4,6,8(14)-triene-3,20-dione
• CAS No.: 23035-53-2
• Molecular Formula: C₂₁H₂₆O₂
• Molecular Weight: 310.436
• Mol file: 23035-53-2.mol

Synonyms:9β,10α-Pregna-4,6,8(14)-triene-3,20-dione

Chemical Property of 9β,10α-Pregna-4,6,8(14)-triene-3,20-dione

Chemical Property:

• PSA: 34.14000
• LogP: 4.56370

Purity/Quality:

98% ^*data from raw suppliers

9β,10α-Pregna-4,6,8(14)-triene-3,20-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 9β,10α-Pregna-4,6,8(14)-triene-3,20-dione is a 3-keto steroid with fluorescent properties that make it useful as a probe for steroid-protein interactions. Also an impurity found in dydrogesterone (D8 26000). 9β,10α-Pregna-4,6,8(14)-triene-3,20-dione is a 3-keto steroid with fluorescent properties that make it useful as a probe for steroid-protein interactions. Also an impurity found in dydrogesterone (D826000).

Technology Process of 9β,10α-Pregna-4,6,8(14)-triene-3,20-dione

There total 3 articles about 9β,10α-Pregna-4,6,8(14)-triene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dydrogesterone (601-33-2,1162-56-7,2640-38-2,3795-24-2,25093-47-4,152-62-5) → 9β,10α-Pregna-4,6,8(14)-trien-3,20-dion (23035-53-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (microbiological transformation)

2: collidine, MeSO₂Cl / dimethylformamide

With 2,3,5-trimethyl-pyridine; methanesulfonyl chloride; In N,N-dimethyl-formamide;

DOI:10.1002/hlca.19690520431

Reference yield:

8-Hydroxy-Δ4,6-9β,10α-pregnadien-3,20-dion (23035-52-1) → 9β,10α-Pregna-4,6,8(14)-trien-3,20-dion (23035-53-2)

Guidance literature:

With 2,3,5-trimethyl-pyridine; methanesulfonyl chloride; In N,N-dimethyl-formamide;

DOI:10.1002/hlca.19690520431

Reference yield:

9-Hydroxy-Δ4,6-9β,10α-pregnadien-3,20-dion (23015-91-0) → 9β,10α-Pregna-4,6,8(14)-trien-3,20-dion (23035-53-2)

Guidance literature:

With trichlorophosphate;

DOI:10.1002/hlca.19690520431

upstream raw materials:

8-Hydroxy-Δ^4,6-9β,10α-pregnadien-3,20-dion

9-Hydroxy-Δ^4,6-9β,10α-pregnadien-3,20-dion

dydrogesterone

Refernces