mono-(6-(1,6-hexamethylenediamine)-6-deoxy)-β-Cyclodextrin

Base Information

• Chemical Name: mono-(6-(1,6-hexamethylenediamine)-6-deoxy)-β-Cyclodextrin
• CAS No.: 131991-61-2
• Molecular Formula: C48H84N2O34
• Molecular Weight: 1233.17
• Mol file: 131991-61-2.mol

Synonyms:mono-(6-(1,6-hexamethylenediamine)-6-deoxy)-β-Cyclodextrin;Mono-(6-(1,6-Hexamethylenediamine)-6-Deoxy)-Beta-Cyclodextrin

Chemical Property of mono-(6-(1,6-hexamethylenediamine)-6-deoxy)-β-Cyclodextrin

Chemical Property:

• Boiling Point: 1517.2±65.0 °C(Predicted)
• PKA: 12.57±0.70(Predicted)
• PSA: 571.87000
• Density: 1.517±0.06 g/cm3(Predicted)
• LogP: -13.02300
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99.0% ^*data from raw suppliers

Mono-(6-(1,6-hexamethylenediamine)-6-deoxy)-β-Cyclodextrin 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of mono-(6-(1,6-hexamethylenediamine)-6-deoxy)-β-Cyclodextrin

There total 1 articles about mono-(6-(1,6-hexamethylenediamine)-6-deoxy)-β-Cyclodextrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

1,6-Hexanediamine (124-09-4) + mono-6-deoxy-6-(p-tolylsulphonyl)-β-cyclodextrin (67217-55-4) → 6A-(6-aminohexylamino)-6A-deoxy-β-cyclodextrin (131991-61-2)

Guidance literature:

In N,N-dimethyl-formamide; at 80 ℃; for 18h; Inert atmosphere;

DOI:10.1021/bm401280z

Reference yield:

morin (480-16-0) + 6A-(6-aminohexylamino)-6A-deoxy-β-cyclodextrin (131991-61-2) → C15H10O7*C48H84N2O34

Guidance literature:

In ethanol; water; at 20 ℃; for 48h;

DOI:10.1007/s10847-016-0631-2

Reference yield:

ibuprofen (15687-27-1,58560-75-1) + 6A-(6-aminohexylamino)-6A-deoxy-β-cyclodextrin (131991-61-2) → C48H84N2O34*C13H18O2

Guidance literature:

In water-d2;

DOI:10.1134/S1070428014080211

upstream raw materials:

1,6-Hexanediamine

mono-6-deoxy-6-(p-tolylsulphonyl)-β-cyclodextrin

Refernces

• 1、 Yang, Xiangliang,Wang, Qin,Xu, Huibi. "Synthesis of novel cyclomaltoheptaose (β-cyclodextrin) derivatives containing the Ebselen key moiety of benzoisoselenazolone". . p. 1309 - 1312. Retrieved 2002.
• 2、 Mentzafos, Dimitris,Terzis, Aris,Coleman, Antony W.,De Rango, Colette. "The crystal structure of 6I-(6-aminohexyl) amino-6I-deoxycyclomaltoheptaose". . p. 125 - 135. Retrieved 1996.
• 3、 Malenkovskaya,Levina,Grachev. "Synthesis and complex formation ability of monomeric and dimeric amphiphilic β-cyclodextrin derivatives". . p. 1194 - 1198. Retrieved 2014.
• 4、 Zhu, Lunan,Zhu, Junchen,Sun, Xiaotong,Wu, Yaling,Wang, Huiying,Cheng, Lingping,Shen, Jiawei,Ke, Yanxiong. "Novel chiral stationary phases based on 3,5-dimethyl phenylcarbamoylated β-cyclodextrin combining cinchona alkaloid moiety". supporting information. p. 1080 - 1090. Retrieved 2020/05/25.