Methyl 3-(Methoxysulfinyl)propanoate

Base Information

• Chemical Name: Methyl 3-(Methoxysulfinyl)propanoate
• CAS No.: 85939-98-6
• Molecular Formula: C₅H₁₀O₄S
• Molecular Weight: 166.198
• Hs Code.: 2930909090
• Mol file: 85939-98-6.mol

Synonyms:Methyl 3-(Methoxysulfinyl)propanoate

Chemical Property of Methyl 3-(Methoxysulfinyl)propanoate

Chemical Property:

• Boiling Point: 92-94 °C(Press: 0.6-1.5 Torr)
• PSA: 71.81000
• Density: 1.274±0.06 g/cm3(Predicted)
• LogP: 0.72530

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl 3-(methoxysulfinyl)propanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 3-(Methoxysulfinyl)propanoate

There total 4 articles about Methyl 3-(Methoxysulfinyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methanol (67-56-1) + Methyl 3-mercaptopropionate (2935-90-2) → methyl 3-(methoxysulfinyl)propanoate (85939-98-6)

Guidance literature:

With N-Bromosuccinimide; In ethyl acetate; at 20 ℃; for 8h; Green chemistry;

DOI:10.1080/17415993.2021.1928669

Reference yield: 66.0%

methanol (67-56-1) + disodium 3-sulfinopropanoate (52329-65-4,85939-96-4) → methyl 3-(methoxysulfinyl)propanoate (85939-98-6)

Guidance literature:

With boron trifluoride diethyl etherate; at 25 ℃; for 2h;

Reference yield: 52.0%

methanol (67-56-1) + sodium 3-methoxy-3-oxo-propane-1-sulfinate (90030-48-1) → methyl 3-(methoxysulfinyl)propanoate (85939-98-6)

Guidance literature:

With sulfuric acid; In dichloromethane; at 25 ℃; for 12.5h; chemoselective reaction; Molecular sieve;

DOI:10.1016/j.tetlet.2017.02.025

upstream raw materials:

methanol

3-(chlorosulfinyl)propanoyl chloride

disodium 3-sulfinopropanoate

sodium 3-methoxy-3-oxo-propane-1-sulfinate

Refernces

• 1、 Tranquilino, Arisson,Andrade, Silvia R.C.P.,da Silva, Ana Paula M.,Menezes, Paulo H.,Oliveira, Roberta A.. "Non-expensive, open-flask and selective catalytic systems for the synthesis of sulfinate esters and thiosulfonates". supporting information. p. 1265 - 1268. Retrieved 2017/03/10.
• 2、 Hoch, J. Mark,Field, Lamar. "Sulfinic Acids and Related Compounds. 14. Derivatives of 3-Sulfinopropanoic Acid". . p. 2601 - 2603. Retrieved 2007/10/02.