(1R,4aα,βS)-Decahydro-2α-hydroxy-β,2,5,5,8aβ-pentamethyl-1-naphthalenepentanoic acid methyl ester

Base Information Edit

Chemical Name:(1R,4aα,βS)-Decahydro-2α-hydroxy-β,2,5,5,8aβ-pentamethyl-1-naphthalenepentanoic acid methyl ester
CAS No.:10267-25-1
Molecular Formula:C₂₁H₃₈O₃
Molecular Weight:338.531
Hs Code.:
Mol file:10267-25-1.mol

Synonyms:(1R,4aα,βS)-Decahydro-2α-hydroxy-β,2,5,5,8aβ-pentamethyl-1-naphthalenepentanoic acid methyl ester;(8R,13S)-8-Hydroxylabdan-15-oic acid methyl ester

Suppliers and Price of (1R,4aα,βS)-Decahydro-2α-hydroxy-β,2,5,5,8aβ-pentamethyl-1-naphthalenepentanoic acid methyl ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1R,4aα,βS)-Decahydro-2α-hydroxy-β,2,5,5,8aβ-pentamethyl-1-naphthalenepentanoic acid methyl ester Edit

Chemical Property:

Melting Point:68.3 - 71.3 °C (hexane)
PSA：46.53000
LogP:4.95940

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1R,4aα,βS)-Decahydro-2α-hydroxy-β,2,5,5,8aβ-pentamethyl-1-naphthalenepentanoic acid methyl ester

There total 10 articles about (1R,4aα,βS)-Decahydro-2α-hydroxy-β,2,5,5,8aβ-pentamethyl-1-naphthalenepentanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 469-11-4
(-)-(3S)-5-((1R,2R,4aS,8aS)-2-hydroxy-2,5,5,8a-tetramethyldecahydro-1-naphthalenyl)-3-methylpentanoic acid

: 18107-18-1
diazomethyl-trimethyl-silane

: 10267-25-1
methyl (5S,8R,9R,10S,13S)-8-hydroxylabdan-15-oate

Guidance literature:: With methanol; In dichloromethane; at 20 ℃; for 0.25h;
DOI:10.1016/j.ejmech.2010.04.007

Reference yield:

: 16736-51-9
8-hydroxy-15,16-dinor-labdan-13-one

: 10267-25-1
methyl (5S,8R,9R,10S,13S)-8-hydroxylabdan-15-oate

Guidance literature:: Multi-step reaction with 2 steps

1: ethoxy-ethynyl magnesium bromide; diethyl ether; benzene / Erwaermen des Reaktionsprodukts mit Methanol

2: platinum; ethanol

With diethyl ether; ethanol; ethoxyethynylmagnesium bromide; platinum; benzene;
DOI:10.1039/jr9600004613