ALPHA-HCH

Base Information

• Chemical Name: ALPHA-HCH
• CAS No.: 319-84-6
• Molecular Formula: C6H6 Cl6
• Molecular Weight: 290.832
• Mol file: 319-84-6.mol

Synonyms:Cyclohexane,1,2,3,4,5,6-hexachloro-, a- (8CI); (?à)-a-HCH; (?à)-a-Hexachlorocyclohexane; a-1,2,3,4,5,6-Hexachlorocyclohexane; a-666; a-BHC; a-Benzenehexachloride; a-Benzohexachloride; a-HCH; a-Hexachloran; a-Hexachlorane; a-Hexachlorcyclohexane; a-Hexachlorocyclohexane; a-Lindane

Chemical Property of ALPHA-HCH

Chemical Property:

• Appearance/Colour: CRYSTALLINE POWDER , WITH CHARACTERISTIC ODOUR
• Vapor Pressure: 0.004mmHg at 25°C
• Melting Point: 156-161 °C(lit.)
• Refractive Index: 1.60-1.626 (589.3 nm 20℃)
• Boiling Point: 288 °C at 760 mmHg
• Flash Point: 157.5 °C
• PSA: 0.00000
• Density: 1.59 g/cm³
• LogP: 3.64440
• Storage Temp.: APPROX 4°C
• Solubility.: Soluble in ethanol, benzene, chloroform (Weast, 1986), cod liver oil, and octanol (Montgomery, 1993)
• Water Solubility.: 2mg/L(25 oC)

Purity/Quality:

98%min ^*data from raw suppliers

α-1,2,3,4,5,6-Hexachlorocyclohexane(>90%) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): TN
• Hazard Codes: T,N,F
• Statements: 21-25-40-50/53-39/23/24/25-23/24/25-11-52/53
• Safety Statements: 22-36/37-45-60-61-16-7

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Physical properties: Brownish to white monoclinic prisms, crystalline solid or powder with a phosgene-like odor (technical grade). An odor threshold concentration of 88 μg/kg was reported by Sigworth (1964).
• Uses: Not produced commercially in the U.S. and its sale is prohibited by the U.S. EPA. α-1,2,3,4,5,6-Hexachlorocyclohexane is an organochloride which is one of the isomers of hexachlorocyclohexane and is an byproduct of insecticide Lindane (L465990).

Technology Process of ALPHA-HCH

There total 19 articles about ALPHA-HCH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → alpha-hexachlorocyclohexane (319-84-6,6108-11-8,8073-23-2)

Guidance literature:

With chlorine;

DOI:10.1021/ja01354a047

Reference yield:

LINDANE (58-89-9,6108-11-8,8073-23-2) → α-3,4,5,6-Tetrachlorocyclohex-1-ene (41992-55-6) + alpha-hexachlorocyclohexane (319-84-6,6108-11-8,8073-23-2) + γ-3,4,5,6-Tetrachlorocyclohex-1-ene (319-81-3,1782-00-9,28810-35-7,28810-37-9,28810-38-0,33875-95-5,41992-55-6,56933-25-6,85687-83-8) + δ-3,4,5,6-Tetrachlorocyclohex-1-ene (319-81-3,1782-00-9,28810-35-7,28810-37-9,28810-38-0,33875-95-5,41992-55-6,56933-25-6,85687-83-8)

Guidance literature:

With TEA; In benzene; at 20 - 25 ℃; Quantum yield; Product distribution; Mechanism; Irradiation;

DOI:10.1021/jo00160a005

Reference yield:

beta-hexachlorocyclohexane (319-85-7,6108-11-8,8073-23-2) → LINDANE (58-89-9,6108-11-8,8073-23-2) + α-3,4,5,6-Tetrachlorocyclohex-1-ene (41992-55-6) + alpha-hexachlorocyclohexane (319-84-6,6108-11-8,8073-23-2) + γ-3,4,5,6-Tetrachlorocyclohex-1-ene (319-81-3,1782-00-9,28810-35-7,28810-37-9,28810-38-0,33875-95-5,41992-55-6,56933-25-6,85687-83-8) + δ-3,4,5,6-Tetrachlorocyclohex-1-ene (319-81-3,1782-00-9,28810-35-7,28810-37-9,28810-38-0,33875-95-5,41992-55-6,56933-25-6,85687-83-8)

Guidance literature:

With TEA; In benzene; at 20 - 25 ℃; Quantum yield; Product distribution; Mechanism; Irradiation;

DOI:10.1021/jo00160a005

upstream raw materials:

alpha-hexachlorocyclohexane

benzene

delta-lindane

LINDANE

Downstream raw materials:

1,3,5-trichlorobenzene

1,2,4-Trichlorobenzene

1,2,3-trichlorobenzene

α-hexachlorocyclohexane

Refernces

• 1、 Cristol. "-". . p. 1894. Retrieved 1949.
• 2、 Stewart,Hanson. "-". . p. 1121,1124, 1127. Retrieved 1931.
• 3、 Moeller, Kattrin,Bretzke, Cornelia,Huehnerfuss, Heinrich,Kallenborn, Roland,Kinkel, Jochen N.,et al.. "Durchlaessigkeit der Blut-Hirn-Schranke von Seehunden fuer das Enantiomer (+)-α-1,2,3,4,5,6-Hexachlorcyclohexan und dessen absolute Konfiguration". . p. 911 - 912. Retrieved 2007/10/02.