1-(3,4-dimethoxyphenyl)pent-4-en-2-ol

Base Information

• Chemical Name: 1-(3,4-dimethoxyphenyl)pent-4-en-2-ol
• CAS No.: 1250342-36-9
• Molecular Formula: C₁₃H₁₈O₃
• Molecular Weight: 222.284
• Mol file: 1250342-36-9.mol

Synonyms:1-(3,4-dimethoxyphenyl)pent-4-en-2-ol

Chemical Property of 1-(3,4-dimethoxyphenyl)pent-4-en-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(3,4-dimethoxyphenyl)pent-4-en-2-ol

There total 2 articles about 1-(3,4-dimethoxyphenyl)pent-4-en-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4-(2,3-epoxypropyl)-1,2-dimethoxybenzene (27602-80-8) + vinyl magnesium bromide (1826-67-1) → 1-(3,4-dimethoxyphenyl)pent-4-en-2-ol (1250342-36-9)

Guidance literature:

With copper(l) iodide; In tetrahydrofuran; at -35 ℃; for 0.75h; Inert atmosphere;

DOI:10.1002/chem.201601471

Reference yield:

3,4-dimethoxyphenylacetaldehyde (5703-21-9) + allyl bromide (106-95-6) → 1-(3,4-dimethoxyphenyl)pent-4-en-2-ol (1250342-36-9)

Guidance literature:

With ammonium chloride; zinc; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1021/jo1008349

Reference yield: 50.0%

2,4-oxazolidinedione (2346-26-1) + 1-(3,4-dimethoxyphenyl)pent-4-en-2-ol (1250342-36-9) → 3-(1-(3,4-dimethoxyphenyl)pent-4-en-2-yl)oxazolidine-2,4-dione

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 13h; Inert atmosphere;

DOI:10.1002/chem.201601471

upstream raw materials:

3,4-dimethoxyphenylacetaldehyde

allyl bromide

4-(2,3-epoxypropyl)-1,2-dimethoxybenzene

vinyl magnesium bromide

Downstream raw materials:

C₂₀H₂₀N₂O₇S

Refernces

• 1、 Fang, Bowen,Zheng, Huaiji,Zhao, Changgui,Jing, Peng,Li, Huilin,Xie, Xingang,She, Xuegong. "Synthesis of the tetracyclic core (ABCE rings) of daphenylline". . p. 8367 - 8373,7. Retrieved 2020/10/15.