4-BUTOXYPHENYLACETONITRILE

Base Information

• Chemical Name: 4-BUTOXYPHENYLACETONITRILE
• CAS No.: 38746-93-9
• Molecular Formula: C12H15NO
• Molecular Weight: 189.257
• Hs Code.: 2926909090
• Mol file: 38746-93-9.mol

Synonyms:Acetonitrile,(p-butoxyphenyl)- (6CI);(4-Butoxyphenyl)acetonitrile;(p-Butoxyphenyl)acetonitrile;4-Butoxybenzeneacetonitrile;

Chemical Property of 4-BUTOXYPHENYLACETONITRILE

Chemical Property:

• Vapor Pressure: 0.000514mmHg at 25°C
• Refractive Index: 1.507
• Boiling Point: 312.9 °C at 760 mmHg
• Flash Point: 132 °C
• PSA: 33.02000
• Density: 1 g/cm³
• LogP: 2.93158

Purity/Quality:

98%min ^*data from raw suppliers

4-butoxyphenylacetonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BUTOXYPHENYLACETONITRILE

There total 9 articles about 4-BUTOXYPHENYLACETONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

sodium cyanide (773837-37-9) + 1-butoxy-4-(chloromethyl)benzene (40141-13-7) → 2-(4-butoxyphenyl)acetonitrile (38746-93-9)

Guidance literature:

In N,N-dimethyl-formamide; at 110 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ja508963v

Reference yield: 73.0%

1-bromo-butane (109-65-9) + 4-cyanomethylphenol (14191-95-8) → 2-(4-butoxyphenyl)acetonitrile (38746-93-9)

Guidance literature:

4-cyanomethylphenol; With sodium hydroxide; In ethanol;

1-bromo-butane; In acetonitrile;

DOI:10.1039/c5cp00696a

Reference yield:

4-cyanomethylphenol (14191-95-8) → 2-(4-butoxyphenyl)acetonitrile (38746-93-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl acetamide; at 70 ℃; for 5h;

upstream raw materials:

1-iodo-butane

4-cyanomethylphenol

1-bromo-butane

tetraethylammoniumcyanide

Downstream raw materials:

2-(4-Butoxy-phenyl)-butyronitrile

4-Butoxy-4'-butoxy-α-cyanostilben

2-(4-Butoxy-phenyl)-pentanoic acid hydroxyamide

2-(4-Butoxy-phenyl)-pentanoic acid ethyl ester

Refernces

• 1、 -. "OXIME SULFONATE COMPOUND, PHOTOACID GENERATOR, RESIST COMPOSITION, CATIONIC POLYMERIZATION INITIATOR, AND CATIONIC POLYMERIZABLE COMPOSITION". Paragraph 0091. . Retrieved 2017/05/02.
• 2、 -. "BREAST CANCER RESISTANCE PROTEIN (BCRP) INHIBITOR". Page/Page column 15-16. . Retrieved 2010/02/14.