Technology Process of 2-(2-Phenylethyl)phenyl azide
There total 4 articles about 2-(2-Phenylethyl)phenyl azide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-(2-phenylethyl)aniline;
With
acetic acid; sodium nitrite;
In
water;
at 0 ℃;
for 2h;
With
sodium azide;
In
water;
at 0 - 20 ℃;
for 1h;
DOI:10.1002/anie.201704260
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine; palladium diacetate; tri-p-tolylphosphite / 20 h / 125 °C
2.1: palladium on activated charcoal; hydrogen / tetrahydrofuran / 20 °C
3.1: acetic acid; sodium nitrite / water / 2 h / 0 °C
3.2: 1 h / 0 - 20 °C
With
palladium on activated charcoal; hydrogen; palladium diacetate; acetic acid; triethylamine; tri-p-tolylphosphite; sodium nitrite;
In
tetrahydrofuran; water;
DOI:10.1002/anie.201704260
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine; palladium diacetate; tri-p-tolylphosphite / 20 h / 125 °C
2.1: palladium on activated charcoal; hydrogen / tetrahydrofuran / 20 °C
3.1: acetic acid; sodium nitrite / water / 2 h / 0 °C
3.2: 1 h / 0 - 20 °C
With
palladium on activated charcoal; hydrogen; palladium diacetate; acetic acid; triethylamine; tri-p-tolylphosphite; sodium nitrite;
In
tetrahydrofuran; water;
DOI:10.1002/anie.201704260
