Heptamethyldisilazane

Base Information

• Chemical Name: Heptamethyldisilazane
• CAS No.: 920-68-3
• Molecular Formula: C7H21NSi2
• Molecular Weight: 175.421
• Hs Code.: 29319090
• European Community (EC) Number: 213-061-5
• DSSTox Substance ID: DTXSID00862468
• Nikkaji Number: J129.698A
• Wikidata: Q17310956
• Mol file: 920-68-3.mol

Synonyms:Heptamethyldisilazane;920-68-3;N,N-bis(trimethylsilyl)methanamine;N,N-Bis(trimethylsilyl)methylamine;Silanamine, N,1,1,1-tetramethyl-N-(trimethylsilyl)-;37074-17-2;N,1,1,1-Tetramethyl-N-(trimethylsilyl)silylamine;Methylbis(trimethylsilyl)amine;Methylamine, 2TMS derivative;bis-(Trimethylsilyl)methylamine;EINECS 213-061-5;n,1,1,1-tetramethyl-n-(trimethylsilyl)silanamine;C7H21NSi2;Heptamethyl disilazane;SCHEMBL234175;Silanamine, N-methyl-N-silyl-;C7-H21-N-Si2;DTXSID00862468;1,1-Bis(trimethylsilyl)methanamine;1,1-bis(trimethylsilyl)methylamine;N-[Bis(trimethylsilyl)methyl]amine;MFCD00008262;AKOS015840163;FS-5058;FT-0626913;FT-0626914;H0954;N-Tetramethyl-N-(trimethylsilyl)silanamine #;D90981;N,1,1,1-Tetramethyl-n-(trmethylslyl)slanamne;S09250;EN300-7645440;J-523194;J-802217;Q17310956;N,N-Bis(trimethylsilyl)methylamine, for GC derivatization, >=97.0% (GC)

Chemical Property of Heptamethyldisilazane

Chemical Property:

• Appearance/Colour: Clear and colorless liquid
• Vapor Pressure: 6.216mmHg at 25°C
• Refractive Index: n20/D 1.421(lit.)
• Boiling Point: 149 °C at 760 mmHg
• PKA: 14.41±0.70(Predicted)
• Flash Point: 43.9 °C
• PSA: 3.24000
• Density: 0.797 g/cm³
• LogP: 2.58800
• Storage Temp.: Flammables area
• Sensitive.: Moisture Sensitive
• Water Solubility.: Decomposes
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 175.12125274
• Heavy Atom Count: 10
• Complexity: 95.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

Heptamethyldisilazane >96.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN([Si](C)(C)C)[Si](C)(C)C

Technology Process of Heptamethyldisilazane

There total 11 articles about Heptamethyldisilazane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

sodium hexamethyldisilazane (1070-89-9) + methyl p-toluene sulfonate (80-48-8) → heptamethyldisilazane (920-68-3)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide; for 1h; Ambient temperature;

Reference yield: 78.0%

Chloromethyltrimethylsilane (2344-80-1) → heptamethyldisilazane (920-68-3)

Guidance literature:

With NaNH₂; In ammonia; NH3 (liquid); (CH3)3SiCH2Cl and NaNH2 in liq. NH3 at 120°C under pressure;;

DOI:10.1021/ja01152a092

Reference yield: 76.0%

trimethylsilyl iodide (16029-98-4) + N,N-dimethyl acetamide (127-19-5,116057-81-9) → N,N-Dimethyltrimethylsilylamine (2083-91-2) + heptamethyldisilazane (920-68-3) + N-methyldiacetamide (1113-68-4) + methyl iodide (74-88-4)

Guidance literature:

In dichloromethane; at 35 ℃; for 5h;

DOI:10.1134/S1070428010060035

upstream raw materials:

chloro-trimethyl-silane

methyltrimethylsilylamine

methylamine

Chloromethyltrimethylsilane

Downstream raw materials:

chloro-trimethyl-silane

1,3-dichloro 1,2,3-trimethyl disilazane

2,4,4,6,6-pentachloro-N-methyl-N-(trimethylsilyl)cyclotriphosphazen-2-amine

ClB{NCH₃Si(CH₃)3}2

Refernces

• 1、 Sauer,Hasek. "-". . p. 244. Retrieved 1946.
• 2、 Shaposhnikov, S. I.,Koidan, G. N.,Marchenko, A. P.,Pinchuk, A. M.. "TRIMETHYLSILYLATION OF COMPOUNDS WITH AN N-Cl BOND". . p. 963 - 966. Retrieved 2007/10/02.