N-Trimethylsilylphthalimide

Base Information Edit

Chemical Name:N-Trimethylsilylphthalimide
CAS No.:10416-67-8
Deprecated CAS:1035455-39-0
Molecular Formula:C11H13 N O2 Si
Molecular Weight:219.315
Hs Code.:2931900090
European Community (EC) Number:233-893-2
NSC Number:252169
UNII:5X68NVE2AO
DSSTox Substance ID:DTXSID5065069
Nikkaji Number:J102.712C
Wikidata:Q81991955
Mol file:10416-67-8.mol

Synonyms:N-Trimethylsilylphthalimide;10416-67-8;Phthalimide, N-(trimethylsilyl)-;2-trimethylsilylisoindole-1,3-dione;N-(Trimethylsilyl)phthalimide;1H-Isoindole-1,3(2H)-dione, 2-(trimethylsilyl)-;Phthalimide, TMS derivative;5X68NVE2AO;2-(trimethylsilyl)isoindoline-1,3-dione;2-(Trimethylsilyl)-1H-isoindole-1,3(2H)-dione;EINECS 233-893-2;NSC 252169;NSC-252169;2-(trimethylsilyl)-2,3-dihydro-1H-isoindole-1,3-dione;Phthalimide-tms;NSC252169;UNII-5X68NVE2AO;C11H13NO2Si;SCHEMBL8744524;DTXSID5065069;C11-H13-N-O2-Si;AKOS024334164;1H-Isoindole-1, 2-(trimethylsilyl)-;FT-0636702;EN300-7350042;2-(trimethylsilyl)-1 h-isoindole-1,3(2h)-dione;A902051;2-(Trimethylsilyl)-1H-isoindole-1,3(2H)-dione #;tert-butyl?4-(5-iodopyridazin-1(2H)-yl)piperidine-1-carboxylate

Suppliers and Price of N-Trimethylsilylphthalimide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
N-(TRIMETHYLSILYL)PHTHALIMIDE AldrichCPR
5mg
$ 115.00

Total 13 raw suppliers

Chemical Property of N-Trimethylsilylphthalimide Edit

Chemical Property:

Vapor Pressure:0.00113mmHg at 25°C
Melting Point:66-67 °C
Boiling Point:300.3°Cat760mmHg
PKA:-1.79±0.20(Predicted)
Flash Point:135.4°C
PSA：37.38000
Density:1.15g/cm³
LogP:2.05540
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:219.071555192
Heavy Atom Count:15
Complexity:284

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-(TRIMETHYLSILYL)PHTHALIMIDE AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)N1C(=O)C2=CC=CC=C2C1=O

Technology Process of N-Trimethylsilylphthalimide

There total 9 articles about N-Trimethylsilylphthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 85-44-9
phthalic anhydride

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 10416-67-8
N-(trimethylsilyl)phthalimide

Guidance literature:: at 130 - 140 ℃;
DOI:10.1023/A:1022976622134 DOI:10.1023/B:RUGC.0000031854.10831.a9

Reference yield: 98.5%

: 136918-14-4,85-41-6
phthalimide

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 10416-67-8
N-(trimethylsilyl)phthalimide

Guidance literature:: With saccharin; at 120 ℃; for 1h; Heating;
DOI:10.1021/jo00141a031

Reference yield: 80.0%

: 100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6
styrene

: 7677-24-9
trimethylsilyl cyanide

: 422508-64-3
1,3-dioxoisoindolin-2-yl 2,3,4,5,6-pentafluorobenzoate

: 10416-67-8
N-(trimethylsilyl)phthalimide

: C₁₆H₈F₅NO₂

Guidance literature:: With tetrakis(acetonitrile)copper(I)tetrafluoroborate; 3,5-difluoro-2,4,6-tris(N-phenylanilino)benzonitrile; C₃₁H₄₈N₂O₆; In acetonitrile; at 5 ℃; for 6h; enantioselective reaction; Schlenk technique; Inert atmosphere; Sealed tube; Irradiation;
DOI:10.1002/anie.202108617