2-hydroxy-5-nonylacetophenone

Base Information

• Chemical Name: 2-hydroxy-5-nonylacetophenone
• CAS No.: 115851-77-9
• Molecular Formula: C₁₇H₂₆O₂
• Molecular Weight: 262.392
• Mol file: 115851-77-9.mol

Synonyms:2-hydroxy-5-nonylacetophenone

Chemical Property of 2-hydroxy-5-nonylacetophenone

Chemical Property:

• Melting Point: 178–182°C
• Boiling Point: 380.6±30.0 °C(Predicted)
• Density: 0.979±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-hydroxy-5-nonylacetophenone

There total 7 articles about 2-hydroxy-5-nonylacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-Nonylphenol (104-40-5) + acetic anhydride (108-24-7) + acetic acid (64-19-7,77671-22-8) → 2-hydroxy-5-nonylacetophenone (115851-77-9)

Guidance literature:

With zinc(II) chloride; at 100 ℃; for 10h; Temperature; Reagent/catalyst;

Reference yield: 63.0%

4-Nonylphenol (104-40-5) + acetyl chloride (75-36-5) → 2-hydroxy-5-nonylacetophenone (115851-77-9)

Guidance literature:

With aluminium trichloride; In 1,2-dichloro-ethane; at 110 - 120 ℃; for 8h;

Reference yield:

C17H26O → 2-hydroxy-5-nonylacetophenone (115851-77-9)

Guidance literature:

With silica gel-supported solid composite chloride salt; In hexane; for 0.0166667h; Microwave irradiation;

upstream raw materials:

4-Nonylphenol

acetyl chloride

Nonanoyl chloride

4-nonanoylphenol

Downstream raw materials:

2-hydroxy-5-nonylacetophenone oxime

(E)-1-(2'-Hydroxy-5'-nonylphenyl)-1-ethanone oxime

Refernces

• 1、 -. "Preparation method of aryl phenolic ketone". Paragraph 0017-0030. . Retrieved 2021/05/05.