Bis(trimethylsilyl)carbodiimide

Base Information

• Chemical Name: Bis(trimethylsilyl)carbodiimide
• CAS No.: 1000-70-0
• Molecular Formula: C7H18 N2 Si2
• Molecular Weight: 186.404
• Hs Code.: 29319090
• European Community (EC) Number: 213-673-2
• DSSTox Substance ID: DTXSID0061379
• Nikkaji Number: J140.843G
• Mol file: 1000-70-0.mol

Synonyms:Bis(trimethylsilyl)carbodiimide;1000-70-0;Carbodiimide, bis(trimethylsilyl)-;BRN 2042082;Silanamine, N,N'-methanetetraylbis[1,1,1-trimethyl-;1,3-Bis(trimethylsilyl)carbodiimide;EINECS 213-673-2;N,N'-Methanediylidenebis(1,1,1-trimethylsilanamine);N,N'-Bis(trimethylsilyl)carbodiimide;N,N'-Methane tetraylbis(1,1,1-trimethylsilanamine);Silanamine, N,N'-methanetetraylbis(1,1,1-trimethyl-;N,N'-Methanetetraylbis(1,1,1-trimethylsilylamine);N,N'-methanetetraylbis[1,1,1-trimethylsilylamine];Silanamine, N,N'-methane tetraylbis(1,1,1-trimethyl-;MFCD00051538;bis-trimethlysilylcarbodiimide;Bis-trimethylsilylcarbodiimide;SCHEMBL27118;C7H18N2Si2;bis-trimethylsilyl-carbodiimide;bis(trimethylsilyl)-carbodiimide;DTXSID0061379;C7-H18-N2-Si2;1,3-bis(trimethylsilyl) carbodiimide;Bis(trimethylsilyl)carbodiimide, 98%;CARBODIIMIDE,BIS-TRIMETHYLSILYL;AKOS015840059;FS-5166;N,N/'-bis(trimethylsilyl)methanediimine;LS-145128;B1368;FT-0623104;Carbodiimide, bis(trimethylsilyl)- (7CI,8CI);D88791;J-000027;N,N'-methanediylidenebis(1,1, 1-trimethylsilanamine);Silanamine, N,N'-methanetetraylbis*1,1,1-trimethyl-;Bis(trimethylsilyl)carbodiimide, purum, >=97.0% (GC);2,2,6,6-tetramethyl-3,5-diaza-2,6-disilahepta-3,4-diene

Chemical Property of Bis(trimethylsilyl)carbodiimide

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 2.43mmHg at 25°C
• Melting Point: -23 ºC
• Refractive Index: n20/D 1.434(lit.)
• Boiling Point: 164 ºC
• Flash Point: 42 ºC
• PSA: 24.72000
• Density: 0.821
• LogP: 2.83010
• Storage Temp.: Flammables area
• Sensitive.: Moisture Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 186.10085165
• Heavy Atom Count: 11
• Complexity: 156

Purity/Quality:

98%,99%, ^*data from raw suppliers

Bis(trimethylsilyl)carbodiimide >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 11-22-36/37/38-10
• Safety Statements: 26-36-37/39-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](C)(C)N=C=N[Si](C)(C)C
• Uses: Reactant for preparation of:4-substituted methoxylbenzoyl-aryl-thiazole analogues as potent and orally bioavailable anticancer agentsO-silylurethanesPorous SiCN materialsLuminescent diketo-pyrrolo-pyrrole analogHard thin films of silicon carbonitride SiCN as potential protection coatings against wear and corrosion of metalsCeramic materials

Technology Process of Bis(trimethylsilyl)carbodiimide

There total 34 articles about Bis(trimethylsilyl)carbodiimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.7%

CYANAMID (420-04-2) + trimethylsilyl cyanide (7677-24-9) → bis(trimethylsilyl)carbodi-imide (1000-70-0)

Guidance literature:

for 0.00555556h;

DOI:10.1021/jo00378a020

Reference yield: 81.0%

CYANAMID (420-04-2) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → bis(trimethylsilyl)carbodi-imide (1000-70-0)

Guidance literature:

In tetrahydrofuran; for 1.5h; Heating;

DOI:10.1002/anie.199703841

Reference yield: 75.7%

chloro-trimethyl-silane (75-77-4) + calcium cyanamide (156-62-7) → bis(trimethylsilyl)carbodi-imide (1000-70-0)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide; for 3h; Heating;

upstream raw materials:

chloro-trimethyl-silane

S-benzylisothiourea hydrochloride

disilver cyanamide

1,3,5-trichloro-2,4,6-triazine

Downstream raw materials:

tris(trimethylsilyl)amine

2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane

phenylthiotrimethylsilane

Bis-(3-nitro-phenyl)-furazan

Refernces

• 1、 Ekouya,A. et al.. "-". . p. 225 - 231. Retrieved 1978.
• 2、 Gabriel, Andreas O.,Riedel, Ralf. "Preparation of Non-Oxidic Silicon Ceramics by an Anhydrous Sol-Gel Process". . p. 384 - 386. Retrieved 1997.
• 3、 Saladino, Raffaele,Neri, Veronica,Crestini, Claudia,Costanzo, Giovanna,Graciotti, Michele,Di Mauro, Ernesto. "Synthesis and degradation of nucleic acid components by formamide and iron sulfur minerals". . p. 15512 - 15518. Retrieved 2008.
• 4、 Stewart, Constantine A.,Dickie, Diane A.,Parkes, Marie V.,Saria, Josephat A.,Kemp, Richard A.. "Reactivity of bis(2,2,5,5-tetramethyl-2,5-disila-1-azacyclopent-1-yl)tin with CO2, OCS, and CS2 and comparison to that of bis[bis(trimethylsilyl)amido]tin". experimental part. p. 11133 - 11141. Retrieved 2011/02/16.