C₂₄H₃₂O₉

Base Information

• Chemical Name: C₂₄H₃₂O₉
• CAS No.: 1335283-51-6
• Molecular Formula: C₂₄H₃₂O₉
• Molecular Weight: 464.513
• Mol file: 1335283-51-6.mol

Synonyms:C₂₄H₃₂O₉

Chemical Property of C₂₄H₃₂O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₃₂O₉

There total 5 articles about C₂₄H₃₂O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

Tetraethylene glycol (112-60-7) + 4-hydroxy-2,5-dimethoxybenzoic acid benzyl ester (1335283-50-5) → C24H32O9 (1335283-51-6)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 23 ℃; for 18h; Inert atmosphere;

DOI:10.1021/ja206339s

Reference yield:

4-bromo-2,5-dimethoxybenzaldehyde (31558-41-5) → C24H32O9 (1335283-51-6)

Guidance literature:

Multi-step reaction with 4 steps

1: dihydrogen peroxide; potassium hydroxide / methanol; water / 1.5 h / 65 °C / Inert atmosphere

2: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium hydroxide; tert-butyl XPhos / 1,4-dioxane; water / 15 h / 80 °C / Inert atmosphere

3: potassium carbonate / N,N-dimethyl-formamide / 18 h / 0 - 23 °C / Inert atmosphere

4: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 18 h / 23 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; di-isopropyl azodicarboxylate; dihydrogen peroxide; potassium carbonate; triphenylphosphine; potassium hydroxide; tert-butyl XPhos; In tetrahydrofuran; 1,4-dioxane; methanol; water; N,N-dimethyl-formamide;

DOI:10.1021/ja206339s

Reference yield:

4-bromo-2,5-dimethoxybenzoic acid (35458-39-0) → C24H32O9 (1335283-51-6)

Guidance literature:

Multi-step reaction with 3 steps

1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium hydroxide; tert-butyl XPhos / 1,4-dioxane; water / 15 h / 80 °C / Inert atmosphere

2: potassium carbonate / N,N-dimethyl-formamide / 18 h / 0 - 23 °C / Inert atmosphere

3: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 18 h / 23 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; di-isopropyl azodicarboxylate; potassium carbonate; triphenylphosphine; potassium hydroxide; tert-butyl XPhos; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide;

DOI:10.1021/ja206339s

upstream raw materials:

Tetraethylene glycol

4-hydroxy-2,5-dimethoxybenzoic acid benzyl ester

4-bromo-2,5-dimethoxybenzaldehyde

4-bromo-2,5-dimethoxybenzoic acid

Downstream raw materials:

C₁₇H₂₆O₉

C₃₄H₄₆N₂O₁₁S

Refernces