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Arbekacin

Base Information Edit
  • Chemical Name:Arbekacin
  • CAS No.:51025-85-5
  • Molecular Formula:C22H44N6O10
  • Molecular Weight:552.626
  • Hs Code.:
  • UNII:G7V6SLI20L
  • DSSTox Substance ID:DTXSID8048319
  • Nikkaji Number:J33.173B
  • Wikipedia:Arbekacin
  • Wikidata:Q4784668
  • NCI Thesaurus Code:C76145
  • Metabolomics Workbench ID:43677
  • ChEMBL ID:CHEMBL426926
  • Mol file:51025-85-5.mol
Arbekacin

Synonyms:1-N-((S)-4-amino-2-hydroxybutyryl)dibekacin;4-amino-2-hydroxybutylyldibekacin;arbekacin;arbekacin sulfate;habekacin;ME1100

Suppliers and Price of Arbekacin
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • American Custom Chemicals Corporation
  • ARBEKACIN 95.00%
  • 1G
  • $ 5054.70
  • American Custom Chemicals Corporation
  • ARBEKACIN 95.00%
  • 100MG
  • $ 1091.48
  • AHH
  • Arbekacin 98%
  • 1g
  • $ 760.00
Total 58 raw suppliers
Chemical Property of Arbekacin Edit
Chemical Property:
  • Vapor Pressure:0mmHg at 25°C 
  • Refractive Index:1.634 
  • Boiling Point:904 °C at 760 mmHg 
  • PKA:13.07±0.70(Predicted) 
  • Flash Point:500.5 °C 
  • Density:1.47 g/cm3 
  • XLogP3:-6.8
  • Hydrogen Bond Donor Count:11
  • Hydrogen Bond Acceptor Count:15
  • Rotatable Bond Count:10
  • Exact Mass:552.31189162
  • Heavy Atom Count:38
  • Complexity:757
Purity/Quality:

99% *data from raw suppliers

ARBEKACIN 95.00% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1CC(C(OC1CN)OC2C(CC(C(C2O)OC3C(C(C(C(O3)CO)O)N)O)NC(=O)C(CCN)O)N)N
  • Isomeric SMILES:C1C[C@H]([C@H](O[C@@H]1CN)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)NC(=O)[C@H](CCN)O)N)N
  • Recent ClinicalTrials:Phase II Study of NPC-14 (Arbekacin Sulfate) to Explore Safety, Tolerability, and Efficacy in Duchenne Muscular Dystrophy
  • Recent NIPH Clinical Trials:The efficacy of AN69 membrane for elimination of aminoglycoside.
  • Description Arbekacin is a semi-synthetic derivative of dibekacin useful in the treatment of bacterial infections. This aminoglycoside is active against a broad spectrum of bacteria, including some of the gentamycin-, kanamycin-, and tobramycin-resistant pathogens. Compared to amikacin and dibekacin, ototoxicity is reportedly milder.
  • Therapeutic Function Antibiotic
Technology Process of Arbekacin

There total 1 articles about Arbekacin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Guidance literature:
Guidance literature:
With sulfuric acid; triethylamine; In 1,4-dioxane; water; at 60 ℃; for 3h;
DOI:10.1038/ja.2015.61
Guidance literature:
With water; triethylamine; isopropyl alcohol; In tetrahydrofuran; at 60 ℃;
DOI:10.3987/COM-07-11081
Refernces Edit
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