Methylcarbamic acid

Base Information

• Chemical Name: Methylcarbamic acid
• CAS No.: 6414-57-9
• Molecular Formula: C2H5 N O2
• Molecular Weight: 75.0672
• Hs Code.: 2935009090
• UNII: 3ALL2Y8QYF
• DSSTox Substance ID: DTXSID70872271
• Nikkaji Number: J549.572E
• Wikidata: Q27104551
• Metabolomics Workbench ID: 52415
• Mol file: 6414-57-9.mol

Synonyms:monomethyl carbamate;N-methylcarbamate;N-methylcarbamate, sodium salt

Chemical Property of Methylcarbamic acid

Chemical Property:

• PSA: 49.33000
• LogP: 0.27470
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 75.032028402
• Heavy Atom Count: 5
• Complexity: 42.9

Purity/Quality:

99%, ^*data from raw suppliers

N-METHYLCARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC(=O)O

Technology Process of Methylcarbamic acid

There total 1 articles about Methylcarbamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + N-methyl-carbamic acid (6414-57-9)

Guidance literature:

With sodium hydroxide; Sulfuric acid, monodecyl ester, sodium salt; at 25 ℃; Further Variations:; Reagents; Kinetics;

DOI:10.1021/jf0505574

Reference yield: 92.0%

N-methyl-carbamic acid (6414-57-9) + indan-1,2,3-trione hydrate (485-47-2) + 1-benzyl-3,5-bis(4-chlorobenzylidene)piperidine-4-one → 1-methyl-4-(4-chlorophenyl)pyrrolo(spiro[2.2']indan-1',3'-dione)spiro[3.3'']-1''-benzyl-5''((E)-(4-chlorophenyl)methylidene)piperidin-4''-one

Guidance literature:

at 80 ℃; for 3h; stereoselective reaction; Ionic liquid; Green chemistry;

DOI:10.1016/j.tetlet.2012.08.060

Reference yield: 92.0%

N-methyl-carbamic acid (6414-57-9) + indan-1,2,3-trione hydrate (485-47-2) + C20H17F2NO (920030-35-9) → C31H26F2N2O3

Guidance literature:

at 80 ℃; for 4h; stereoselective reaction; Ionic liquid; Green chemistry;

DOI:10.1016/j.tetlet.2012.08.060

upstream raw materials:

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate

Refernces