Benzil monohydrazone

Base Information

• Chemical Name: Benzil monohydrazone
• CAS No.: 5344-88-7
• Molecular Formula: C14H12N2O
• Molecular Weight: 224.262
• Hs Code.: 29280090
• European Community (EC) Number: 226-292-1
• NSC Number: 5323,1171
• Mol file: 5344-88-7.mol

Synonyms:Benzil monohydrazone;5344-88-7;Hydrazonodeoxybenzoin;2-hydrazinylidene-1,2-diphenylethan-1-one;Benzilmonohydrazone;EINECS 226-292-1;Ethanedione, diphenyl-, monohydrazone;(2E)-2-hydrazinylidene-1,2-diphenylethanone;1, HYDRAZONE;SCHEMBL17485943;CDQPGWNBSOSEMZ-DTQAZKPQSA-;NSC1171;NSC5323;CDQPGWNBSOSEMZ-DTQAZKPQSA-N;HMS1766B22;2-Hydrazono-1,2-diphenyl-ethanone;NSC 1171;NSC 5323;NSC-1171;NSC-5323;BBL027649;MFCD00007625;STL373493;AKOS000119485;VS-08574;1,2-Diphenyl-1,2-ethanedione 1-hydrazone;CS-0236826;EN300-17365;1,2-Ethanedione, 1,2-diphenyl-, 1-hydrazone;(2E)-2-hydrazinylidene-1,2-di(phenyl)ethanone;(2E)-2-hydrazinylidene-1,2-diphenylethan-1-one;Z56922156;InChI=1/C14H12N2O/c15-16-13(11-7-3-1-4-8-11)14(17)12-9-5-2-6-10-12/h1-10H,15H2/b16-13+

Chemical Property of Benzil monohydrazone

Chemical Property:

• Appearance/Colour: 24/25
• Vapor Pressure: 2.6E-06mmHg at 25°C
• Melting Point: 150-152 °C(lit.)
• Refractive Index: 1.594
• Boiling Point: 390.7 °C at 760 mmHg
• Flash Point: 190.1 °C
• PSA: 55.45000
• Density: 1.12 g/cm³
• LogP: 2.93260
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 224.094963011
• Heavy Atom Count: 17
• Complexity: 287

Purity/Quality:

99% ^*data from raw suppliers

2-hydrazono-1,2-diphenylethanone ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Aromatics (Nitrogen)
• Canonical SMILES: C1=CC=C(C=C1)C(=NN)C(=O)C2=CC=CC=C2
• Isomeric SMILES: C1=CC=C(C=C1)/C(=N\N)/C(=O)C2=CC=CC=C2

Technology Process of Benzil monohydrazone

There total 11 articles about Benzil monohydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzil (134-81-6) → benzil monohydrazone (5344-88-7)

Guidance literature:

With hydrazine hydrate; In ethanol; at 25 ℃; for 2h;

DOI:10.3906/kim-1902-38

Reference yield: 89.0%

benzil (134-81-6) → (E)-2-hydrazono-1,2-diphenylethanone (5344-88-7)

Guidance literature:

With hydrazine hydrate; In ethanol; for 0.0833333h; Reflux;

DOI:10.1007/s11224-011-9817-9

Reference yield:

(E)-benzil monooxime (574-15-2,5351-34-8) → benzil monohydrazone (5344-88-7)

Guidance literature:

With ethanol; hydrazine hydrate;

upstream raw materials:

(E)-benzil monooxime

hydrazinium monoacetate

benzil

2-diazo-1,2-diphenylethan-1-one

Downstream raw materials:

N-(3-oxo-5,6-diphenyl-2,3-dihydro-pyridazin-4-yl)-benzamide

phenyl benzyl ketone

benzil monoazine

erythro-2-amino-1,2-diphenylethanol

Refernces

• 1、 Tan, Xue-Jie,Wang, Di,Lei, Xu-Gang,Chen, Jun-Peng. "Theoretical insight into the disordered structure of (Z)-2-[(E)-(4-methoxybenzylidene)hydrazinylidene]-1,2-diphenylethanone: The role of noncovalent interactions". . p. 1058 - 1067. Retrieved 2018.
• 2、 Faramarzi, Mohammad Ali,Firoozpour, Loghman,Foroumadi, Alireza,Moghimi, Setareh,Mojtabavi, Somayeh,Sadat Ebrahimi, Seyed Esmaeil,Safari, Fatemeh,Salarinejad, Somayeh,Toolabi, Mahsa. "Design and synthesis of novel pyridazine N-aryl acetamides: In-vitro evaluation of α-glucosidase inhibition, docking, and kinetic studies". . . Retrieved 2020/07/21.
• 3、 Aydiner, Burcu. "Coumarin-based benzilmonohydrazone as a new proton-sensitive fluorescence dye: Synthesis and investigation of photophysical and acidochromic properties". . p. 1086 - 1097. Retrieved 2019/09/10.