Technology Process of 3-phenyl-3H-imidazo[4,5-c]pyridine
There total 5 articles about 3-phenyl-3H-imidazo[4,5-c]pyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; potassium phosphate;
In
tert-butyl alcohol;
at 110 ℃;
for 6.5h;
Reagent/catalyst;
Schlenk technique;
Inert atmosphere;
DOI:10.1021/jo500064j
- Guidance literature:
-
With
copper(I) oxide; 8-quinolinol; caesium carbonate;
In
dimethyl sulfoxide;
at 140 ℃;
for 1h;
Inert atmosphere;
Microwave irradiation;
DOI:10.1021/acs.jmedchem.6b00989
- Guidance literature:
-
Multi-step reaction with 2 steps
1: trifluoroacetic acid / dichloromethane / 24 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
2: potassium phosphate; tris(dibenzylideneacetone)dipalladium(0) chloroform complex / tert-butyl alcohol / 6.5 h / 110 °C / Schlenk technique; Inert atmosphere
With
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; potassium phosphate; trifluoroacetic acid;
In
dichloromethane; tert-butyl alcohol;
DOI:10.1021/jo500064j
