Trimorpholinophosphine oxide

Base Information

• Chemical Name: Trimorpholinophosphine oxide
• CAS No.: 4441-12-7
• Molecular Formula: C12H24N3O4P
• Molecular Weight: 305.314
• Hs Code.: 29349990
• European Community (EC) Number: 224-662-7
• NSC Number: 41250
• UNII: K6FWD4S4ZD
• DSSTox Substance ID: DTXSID00196159
• Nikkaji Number: J205.823E
• Wikidata: Q72514647
• Mol file: 4441-12-7.mol

Synonyms:Trimorpholinophosphine oxide;4441-12-7;4,4',4''-phosphoryltrimorpholine;4-dimorpholin-4-ylphosphorylmorpholine;Phosphoric Trimorpholide;Tri(4-morpholinyl)phosphine oxide;K6FWD4S4ZD;4-[bis(morpholin-4-yl)phosphoroso]morpholine;Tri(4-Morpholino)phosphine oxide;MFCD00047406;NSC-41250;Phosphoric acid trimorpholide;C12H24N3O4P;Tris(4-morpholino)phosphine oxide;NSC41250;UNII-K6FWD4S4ZD;PHOSPHORYL TRIMORPHOLIDE;SCHEMBL1276983;DTXSID00196159;Tris-(morpholino)-phosphine oxide;PHOSPHORIC ACIDTRIMORPHOLIDE;4-(dimorpholinophosphoryl)morpholine;BCP22584;EINECS 224-662-7;NSC 41250;STK664711;AKOS001750430;TRIS(MORPHOLINO)PHOSPHINE OXIDE;CS-W002230;DS-2096;4,4',4''-Phosphinylidynetrismorpholine;SY019073;Trimorpholinophosphine oxide, 99% (HPLC);AI3-61409;FT-0635298;Morpholine, 4,4,'4''-phosphinylidynetris-;T2748;Morpholine, 4-[di(4-morpholinyl)phosphinyl]-;EN300-7388641;A924153;J-513958;MORPHOLINE, 4,4',4''-PHOSPHINYLIDYNETRIS-

Chemical Property of Trimorpholinophosphine oxide

Chemical Property:

• Vapor Pressure: 0-0Pa at 20-50℃
• Melting Point: 188-190 °C
• Refractive Index: 1.5540 (estimate)
• Boiling Point: 476.4 °C at 760 mmHg
• PKA: 1.61±0.20(Predicted)
• Flash Point: 241.9 °C
• PSA: 64.29000
• Density: 1.3 g/cm³
• LogP: -0.09520
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Water Solubility.: 607.20g/L(25 oC)
• XLogP3: -1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 3
• Exact Mass: 305.15044325
• Heavy Atom Count: 20
• Complexity: 300

Purity/Quality:

99.9% ^*data from raw suppliers

Tri(4-morpholinyl)phosphineOxide ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1P(=O)(N2CCOCC2)N3CCOCC3
• Uses: Trimorpholinophosphine oxide (morPO) is used a coordination chemistry of phosphoryl compounds. It forms the complexes [Fe(morPO)nX2](n =1/2-4,X=BF4，NO3, NCS,Cl, Br, or I) in which the ligand morPO is co-ordinated by the oxygen atom.

Technology Process of Trimorpholinophosphine oxide

There total 5 articles about Trimorpholinophosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

trimorpholylmethane (22630-09-7) + di-morpholin-4-yl-phosphinic acid chloride (7264-90-6) → tris(morpholino)phenylphosphine oxide (4441-12-7)

Guidance literature:

In benzene; at 60 ℃; for 1h;

Reference yield: 50.0%

trimorpholylmethane (22630-09-7) → tris(morpholino)phenylphosphine oxide (4441-12-7)

Guidance literature:

With trichlorophosphate; In benzene; for 1h;

Reference yield:

morpholine (110-91-8,99108-56-2) → tris(morpholino)phenylphosphine oxide (4441-12-7)

Guidance literature:

With trichlorophosphate;

DOI:10.1021/ja01259a018

upstream raw materials:

morpholine

trimorpholylmethane

di-morpholin-4-yl-phosphinic acid chloride

P,P-dichlorophenylphosphine oxide

Refernces

• 1、 Tarahhomi, Atekeh,van der Lee, Arie. "Synthesis and crystal structures of new phosphoric triamides: study of intermolecular interactions by semi-empirical calculations and Hirshfeld surface analysis". . p. 1759 - 1776. Retrieved 2018.
• 2、 Shevchenko, M. V.,Kukhar', V. P.. "AMIDATION OF HALOGEN DERIVATIVES OF PHOSPHORUS WITH 4,4',4''-METHYLIDYNETRISMORPHOLINE". . p. 1336 - 1340. Retrieved 2007/10/02.