o-Diacetoxymethyl-benzylbromid

Base Information

• Chemical Name: o-Diacetoxymethyl-benzylbromid
• CAS No.: 37803-24-0
• Molecular Formula: C₁₂H₁₃BrO₄
• Molecular Weight: 301.137
• Mol file: 37803-24-0.mol

Synonyms:o-Diacetoxymethyl-benzylbromid

Chemical Property of o-Diacetoxymethyl-benzylbromid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of o-Diacetoxymethyl-benzylbromid

There total 3 articles about o-Diacetoxymethyl-benzylbromid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-diacetoxymethyltoluene (31675-37-3) → o-Diacetoxymethyl-benzylbromid (37803-24-0)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; Reflux;

DOI:10.1002/ejoc.201001309

Reference yield:

2-methylphenyl aldehyde (529-20-4) → o-Diacetoxymethyl-benzylbromid (37803-24-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / water

2: N-Bromosuccinimide

With N-Bromosuccinimide; sulfuric acid; In water;

DOI:10.1039/c5ob02405f

Reference yield:

→ o-Diacetoxymethyl-benzylbromid (37803-24-0)

Guidance literature:

o-Tolualdehyd, 1.) Ac2O/H+, 2.) NBS/CCl4;

upstream raw materials:

2-diacetoxymethyltoluene

2-methylphenyl aldehyde

Downstream raw materials:

C₁₈H₁₇BrS₂

β-brazan

2-Acetoxymethyl-benzyliden-diacetat

5-methyltetraphene

Refernces

• 1、 Sureshbabu, Radhakrishnan,Saravanan, Velu,Dhayalan, Vasudevan,Mohanakrishnan, Arasambattu K.. "Lewis acid mediated one-pot synthesis of aryl/heteroaryl-fused carbazoles involving a cascade Friedel-Crafts alkylation/electrocyclization/aromatization reaction sequence". experimental part. p. 922 - 935. Retrieved 2011/04/22.