31675-37-3

Basic information

• Product Name: Methanediol, (2-methylphenyl)-, diacetate
• Synonyms: 2-Methyl-benzyliden-diacetat;2-diacetoxymethyltoluene;o-Diacetoxymethyl-toluol
• CAS NO: 31675-37-3
• Molecular Formula: C12H14O4
• Molecular Weight: 222.241
• Mol File: 31675-37-3.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Methanediol, (2-methylphenyl)-, diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methanediol, (2-methylphenyl)-, diacetate(31675-37-3)
• EPA Substance Registry System: Methanediol, (2-methylphenyl)-, diacetate(31675-37-3)

Safety Data

• Hazardous Substances Data: 31675-37-3(Hazardous Substances Data)

Upstream product

• 611-15-4 1-methyl-2-vinyl-benzene 
• 108-24-7 acetic anhydride 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 60633-91-2 2-(bromomethyl)benzaldehyde 
• 148875-99-4 2-Acetoxymethyl-benzyliden-diacetat 
• 2319-96-2 5-methyltetraphene 
• 37803-24-0 o-Diacetoxymethyl-benzylbromid 
• 243-46-9 benzo[b]naphtho[2,3-d]thiophene 
• 243-42-5 β-brazan 
• 1273320-75-4 C₂₄H₁₇BrS₂ 
• 1273320-74-3 C₁₈H₁₇BrS₂ 
• 418803-02-8 ethyl 6-methyl-4-(2-methylphenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 430452-86-1 ethyl 6-methyl-2-thioxo-4-(o-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 529-20-4 2-methylphenyl aldehyde 
• 17373-93-2 2-methylbenzyl acetate 

Relevant articles and documents

One-pot synthesis of 1H-isochromenes and 1,2-dihydroisoquinolines by a sequential isocyanide-based multicomponent/Wittig reaction

A one-pot synthesis of 1H-isochromenes and 1,2-dihydroisoquinolines by a I-MCR/Wittig sequence was developed. The reaction of phosphonium salt 5, an acid, an amine (or without), and an isocyanide gave the 1H-isochromenes 7 or 1,2-dihydroisoquinolines 9 in

Zinc zirconium phosphate as an efficient catalyst for chemoselective synthesis of 1,1-diacetates under solvent-free conditions

In the present study, a mild, rapid, and efficient method for the protection of aldehydes with acetic anhydride (AA) in the presence of zinc zirconium phosphate (ZPZn) as a nano catalyst, at room temperature is reported. Selective conversion of aldehydes was observed in the presence of ketones. Under these conditions, different aldehydes bearing electron-withdrawing and electron-donating substituents were reacted with AA and the corresponding 1,1-diacetates (acylals) were obtained in high to excellent yields. The steric and electronic properties of the different substrates had a significant influence on the reaction conditions. Also, the deprotection of 1,1-diacetates has been achieved using this catalyst in water. This nanocatalyst was characterized by several physico-chemical techniques. It was recovered easily from the reaction mixture, regenerated and reused at least 7 times without significant loss in catalytic activity. This protocol has the advantages of easy availability, stability, reusability of the eco-friendliness, chemoselectivity, simple experimental and work-up procedure, solvent-free conditions and usage of only a stoichiometric amount of AA.

Sulfonated rice husk ash (RHA-SO3H): A highly powerful and efficient solid acid catalyst for the chemoselective preparation and deprotection of 1,1-diacetates

Rice husk ash (RHA), as a source of amorphous silica, was treated with chlorosulfonic acid and sulfonated rice husk ash (RHA-SO3H) as a highly powerful solid acid catalyst was obtained and characterized with a variety of techniques including IR, TGA, SEM, XRD, pH analysis, Hammett acidity function and BET method. This solid acid showed excellent catalytic activity for the protection and deprotection of aldehydes with Ac2O at room temperature under solvent free conditions. The procedure gave the products in excellent yields in very short reaction times and good to high yields. Also this catalyst can be reused for several times without loss of its catalytic activity.