2319-96-2 Usage
Description
5-METHYLBENZ[A]ANTHRACENE, also known as 5-Methylchrysene, is a monomethylated polycyclic aromatic hydrocarbon (PAH) characterized by its carcinogenic activity. It is a potent mutagen and has been widely used in various research applications due to its ability to induce cancer in experimental models.
Uses
Used in Research and Development:
5-METHYLBENZ[A]ANTHRACENE is used as a research chemical for studying the mechanisms of carcinogenesis and mutagenesis. Its application in this field is crucial for understanding the effects of PAHs on human health and the environment.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-METHYLBENZ[A]ANTHRACENE is used as a reference compound for the development of new drugs and therapies targeting cancer. Its carcinogenic properties make it a valuable tool for testing the efficacy of potential cancer treatments.
Used in Environmental Monitoring:
5-METHYLBENZ[A]ANTHRACENE is also used in environmental monitoring and assessment, as it is a common pollutant found in air, water, and soil samples. Its detection and quantification help in evaluating the level of contamination and the potential health risks associated with exposure to PAHs.
Used in Toxicology Studies:
5-METHYLBENZ[A]ANTHRACENE is employed in toxicology studies to investigate the toxic effects of PAHs on various organisms, including humans. These studies contribute to the development of safety guidelines and regulations to minimize the adverse health effects of PAH exposure.
Used in Cancer Research:
In cancer research, 5-METHYLBENZ[A]ANTHRACENE is used as a model compound to study the initiation and progression of cancer. Its ability to induce tumors in experimental models helps researchers understand the molecular mechanisms underlying cancer development and identify potential therapeutic targets.
Check Digit Verification of cas no
The CAS Registry Mumber 2319-96-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,1 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2319-96:
(6*2)+(5*3)+(4*1)+(3*9)+(2*9)+(1*6)=82
82 % 10 = 2
So 2319-96-2 is a valid CAS Registry Number.
InChI:InChI=1/C19H14/c1-13-10-16-11-14-6-2-3-7-15(14)12-19(16)18-9-5-4-8-17(13)18/h2-12H,1H3
2319-96-2Relevant articles and documents
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Anet,F.A.L.,Bavin,P.M.G.
, p. 240 - 243 (1960)
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Synthesis of annulated arenes and heteroarenes by hydriodic acid and red phosphorus mediated reductive cyclization of 2-(Hetero)aroylbenzoic acids or 3-(Hetero)arylphthalides
Rafiq, Settu Muhamad,Mohanakrishnan, Arasambattu K.
supporting information, p. 362 - 370 (2017/02/10)
Annulated arenes and hetarenes were prepared in good to very good yields by hydriodic acid/red phosphorus mediated reductive cyclization of 3-(hetero)aryl phthalides. The reductive cyclization also proceeded successfully with 2-aroylbenzoic acids and 2-aroylnaphthoic acids.
Lewis acid mediated one-pot synthesis of aryl/heteroaryl-fused carbazoles involving a cascade Friedel-Crafts alkylation/electrocyclization/aromatization reaction sequence
Sureshbabu, Radhakrishnan,Saravanan, Velu,Dhayalan, Vasudevan,Mohanakrishnan, Arasambattu K.
, p. 922 - 935 (2011/04/22)
A Lewis-acid-mediated domino reaction of 2/3-(bromomethyl)indoles with arenes/heteroarenes led to the formation of the corresponding annulated carbazoles. This three-step one-pot transformation proceeds by sequential Lewis acid catalysed Friedel-Crafts alkylation, electrocyclization and aromatization reactions. The strategy is highly efficient for the assembly of complex aryl/heteroaryl-fused carbazoles.
