Miroprofen

Base Information

• Chemical Name: Miroprofen
• CAS No.: 55843-86-2
• Molecular Formula: C16H14N2O2
• Molecular Weight: 266.299
• Hs Code.: 2933990090
• UNII: S00I5XG484
• DSSTox Substance ID: DTXSID30866515
• Nikkaji Number: J11.048E
• Wikipedia: Miroprofen
• Wikidata: Q3858912
• NCI Thesaurus Code: C90910
• Pharos Ligand ID: 5786Q2GM9RJK
• ChEMBL ID: CHEMBL2106551
• Mol file: 55843-86-2.mol

Synonyms:2-(4-(2-imidazo(1,2-a)pyridyl)phenyl)propionic acid;55843-86-2;miroprofen;Y-9213

Chemical Property of Miroprofen

Chemical Property:

• Refractive Index: 1.6240 (estimate)
• Boiling Point: °Cat760mmHg
• PKA: 3.79±0.10(Predicted)
• Flash Point: °C
• PSA: 54.60000
• Density: 1.24g/cm³
• LogP: 3.18940
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 266.105527694
• Heavy Atom Count: 20
• Complexity: 352

Purity/Quality:

99% ^*data from raw suppliers

2-(4-IMIDAZO[1,2-A]PYRIDIN-2-YLPHENYL)PROPANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=C(C=C1)C2=CN3C=CC=CC3=N2)C(=O)O

Technology Process of Miroprofen

There total 2 articles about Miroprofen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-imidazo[1,2-a]pyridin-2-yl-phenyl)-propionic acid ethyl ester (55843-79-3) → 2 [4 (imidazo[1,2 a]pyridin 2 yl)phenyl]propionic acid (55843-86-2)

Guidance literature:

With sodium hydroxide; In ethanol; water;

Reference yield:

→ 2 [4 (imidazo[1,2 a]pyridin 2 yl)phenyl]propionic acid (55843-86-2)

Guidance literature:

Ethylester VIIa2/wss.ethanol.NaOH, Δ;

Reference yield:

2-(N,N-dimethylamino)ethanol (108-01-0) + p-toluenesulfonyl chloride (98-59-9) + 2 [4 (imidazo[1,2 a]pyridin 2 yl)phenyl]propionic acid (55843-86-2) + methyl iodide (74-88-4) → 2-dimethylaminoethyl 2-[4-(imidazo[1,2-a]pyridin-2-yl)phenyl]propionate methiodide monohydrate

Guidance literature:

With pyridine; In ethyl acetate;

upstream raw materials:

2-(4-imidazo[1,2-a]pyridin-2-yl-phenyl)-propionic acid ethyl ester

Refernces