4-NITROBENZOIC ANHYDRIDE

Base Information

• Chemical Name: 4-NITROBENZOIC ANHYDRIDE
• CAS No.: 902-47-6
• Molecular Formula: C14H8 N2 O7
• Molecular Weight: 316.227
• Mol file: 902-47-6.mol

Synonyms:Benzoicacid, 4-nitro-, anhydride (9CI); Benzoic acid, p-nitro-, anhydride(6CI,7CI,8CI); 4-Nitrobenzoic acid anhydride; 4-Nitrobenzoic anhydride; NSC147485; p-Nitrobenzoic acid anhydride; p-Nitrobenzoic anhydride

Chemical Property of 4-NITROBENZOIC ANHYDRIDE

Chemical Property:

• Vapor Pressure: 8E-12mmHg at 25°C
• Melting Point: 195-195.5 °C
• Boiling Point: 542.3°Cat760mmHg
• Flash Point: 251.3°C
• PSA: 135.01000
• Density: 1.502g/cm³
• LogP: 3.54660

Purity/Quality:

99% ^*data from raw suppliers

4-Nitrobenzoic anhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-NITROBENZOIC ANHYDRIDE

There total 31 articles about 4-NITROBENZOIC ANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-nitro-benzoyl chloride (122-04-3) → p-nitrobenzoic anhydride (902-47-6)

Guidance literature:

With water; triethylamine; In acetone; at 20 ℃; for 1h;

DOI:10.1021/ol0524048

Reference yield: 97.0%

4-nitro-benzoic acid (62-23-7) → p-nitrobenzoic anhydride (902-47-6)

Guidance literature:

With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1055/s-1981-29544

Reference yield: 96.0%

potassium 4-nitrobenzoate (15922-01-7) + 4-nitro-benzoic acid (62-23-7) → p-nitrobenzoic anhydride (902-47-6)

Guidance literature:

4-nitro-benzoic acid; With trichloroisocyanuric acid; triphenylphosphine; In dichloromethane; at 0 - 20 ℃;

potassium 4-nitrobenzoate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1515/chempap-2015-0042

upstream raw materials:

pyridine

4-nitro-benzoyl chloride

acetaldehyde p-nitrophenylhydrazone

1-chloro-3-ethylpentan-3-ol

Downstream raw materials:

3-amino-5-p-nitrobenzamido-1,2,4-triazole

3,5-bis-p-nitrobenzamido-1,2,4-triazole

4-Nitro-benzoic acid (3S,5R)-3-(4-chloro-phenyl)-3-imidazol-1-ylmethyl-2-methyl-isoxazolidin-5-ylmethyl ester

4-Nitro-benzoic acid (3S,5S)-3-(4-chloro-phenyl)-3-imidazol-1-ylmethyl-2-methyl-isoxazolidin-5-ylmethyl ester

Refernces

• 1、 Sauuders et al.. "". . p. 2507. Retrieved 1975.
• 2、 Kaur, Avneet,Pathak, Dharam P.,Sharma, Vidushi,Wakode, Sharad. "Synthesis, molecular docking, and pharmacological evaluation of N-(2-(3,5-dimethoxyphenyl)benzoxazole-5-yl)benzamide derivatives as selective COX-2 inhibitors and anti-inflammatory agents". . . Retrieved 2018/05/15.
• 3、 Kaur, Avneet,Pathak, Dharam P.,Sharma, Vidushi,Narasimhan, Balasubramanian,Sharma, Prateek,Mathur, Rajani,Wakode, Sharad. "Synthesis, biological evaluation and docking study of N-(2-(3,4,5-trimethoxybenzyl)benzoxazole-5-yl) benzamide derivatives as selective COX-2 inhibitor and anti-inflammatory agents". . p. 191 - 202. Retrieved 2018/08/23.