benzyl (4S)-4-methylhexyl ether

Base Information

• Chemical Name: benzyl (4S)-4-methylhexyl ether
• CAS No.: 1580449-05-3
• Molecular Formula: C₁₄H₂₂O
• Molecular Weight: 206.328
• Mol file: 1580449-05-3.mol

Synonyms:benzyl (4S)-4-methylhexyl ether

Chemical Property of benzyl (4S)-4-methylhexyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of benzyl (4S)-4-methylhexyl ether

There total 3 articles about benzyl (4S)-4-methylhexyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C16H26O7S2 → benzyl (4S)-4-methylhexyl ether (1580449-05-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h; Reflux;

DOI:10.1134/S1070428014020043

Reference yield:

(3S,5R)-6-(benzyloxy)-3-methylhexane-1,5-diol (1580448-84-5) → benzyl (4S)-4-methylhexyl ether (1580449-05-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / diethyl ether / 2 h / 0 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / Reflux

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; diethyl ether;

DOI:10.1134/S1070428014020043

Reference yield:

(4R,6R)-6-(benzyloxymethyl)-4-methyltetrahydro-2H-pyran-2-one (130129-23-6) → benzyl (4S)-4-methylhexyl ether (1580449-05-3)

Guidance literature:

Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / diethyl ether / 0.5 h

2: triethylamine / diethyl ether / 2 h / 0 °C

3: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / Reflux

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; diethyl ether;

DOI:10.1134/S1070428014020043

upstream raw materials:

(3S,5R)-6-(benzyloxy)-3-methylhexane-1,5-diol

(4R,6R)-6-(benzyloxymethyl)-4-methyltetrahydro-2H-pyran-2-one

Downstream raw materials:

(S)-4-methyl-1-hexanol

Refernces