2-(2-methyl-6-styrylphenyl)-pyridine

Base Information

• Chemical Name: 2-(2-methyl-6-styrylphenyl)-pyridine
• CAS No.: 945721-46-0
• Molecular Formula: C₂₀H₁₇N
• Molecular Weight: 271.362
• Mol file: 945721-46-0.mol

Synonyms:2-(2-methyl-6-styrylphenyl)-pyridine

Chemical Property of 2-(2-methyl-6-styrylphenyl)-pyridine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-(2-methyl-6-styrylphenyl)-pyridine

There total 11 articles about 2-(2-methyl-6-styrylphenyl)-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-(2-methylphenyl)pyridine (10273-89-9) + styryl acetate (10521-96-7) → 2-(2-methyl-6-styrylphenyl)-pyridine (945721-46-0)

Guidance literature:

ruthenium cycloocta-1,5-diene cycloocta-1,3,5-triene; In 1,4-dioxane; at 20 - 100 ℃; for 40h;

Reference yield: 83.0%

2-(2-methylphenyl)pyridine (10273-89-9) + isopropyl β-styrylcarbonate → 2-(2-methyl-6-styrylphenyl)-pyridine (945721-46-0)

Guidance literature:

With (η6-1,3,5-cyclooctatriene)(η4-1,5-cyclooctadiene)ruthenium(0); In para-xylene; at 150 ℃; for 48h; Time; regioselective reaction;

DOI:10.1246/cl.140006

Reference yield: 64.0%

2-(2-methylphenyl)pyridine (10273-89-9) + cinnamic acid anhydride (538-56-7) → 2-(2-methyl-6-styrylphenyl)-pyridine (945721-46-0)

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; sodium carbonate; In o-xylene; at 145 ℃; for 12h; regioselective reaction; Inert atmosphere; Molecular sieve;

DOI:10.1021/ol9000729

upstream raw materials:

2-(2-methylphenyl)pyridine

styryl acetate

cinnamic acid anhydride

cinnamoyl chloride

Refernces

• 1、 Ogiwara, Yohei,Kochi, Takuya,Kakiuchi, Fumitoshi. "Ruthenium-catalyzed ortho-selective aromatic CH alkenylation with alkenyl carbonates". supporting information. p. 667 - 669. Retrieved 2014/05/20.
• 2、 -. "METHOD OF PRODUCING AROMATIC COMPOUND". Page/Page column 6. . Retrieved 2009/03/07.