Technology Process of 1,1-diethyl-4-(phenyl-4-hydroxy)-homopiperazinium tosylate
There total 5 articles about 1,1-diethyl-4-(phenyl-4-hydroxy)-homopiperazinium tosylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
dichloromethane;
at 40 ℃;
for 43h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium tert-butylate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 18 h / 90 °C
2: acetone / 41 h / Reflux
3: palladium 10% on activated carbon; hydrogen / dichloromethane / 43 h / 40 °C
With
tris-(dibenzylideneacetone)dipalladium(0); palladium 10% on activated carbon; potassium tert-butylate; hydrogen; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
dichloromethane; acetone; toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: acetone / 41 h / Reflux
2: palladium 10% on activated carbon; hydrogen / dichloromethane / 43 h / 40 °C
With
palladium 10% on activated carbon; hydrogen;
In
dichloromethane; acetone;
