Technology Process of 1-(benzyl carboxy)-4-ethyl-homopiperazine
There total 1 articles about 1-(benzyl carboxy)-4-ethyl-homopiperazine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium carbonate;
In
water; tert-butyl alcohol;
at 0 ℃;
for 2.5h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 17 h / 20 °C
2: potassium tert-butylate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 18 h / 90 °C
With
tris-(dibenzylideneacetone)dipalladium(0); palladium 10% on activated carbon; potassium tert-butylate; hydrogen; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
ethyl acetate; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 17 h / 20 °C
2: potassium tert-butylate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 18 h / 90 °C
3: acetone / 41 h / Reflux
With
tris-(dibenzylideneacetone)dipalladium(0); palladium 10% on activated carbon; potassium tert-butylate; hydrogen; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
ethyl acetate; acetone; toluene;
