Diphenylmaleic anhydride

Base Information

• Chemical Name: Diphenylmaleic anhydride
• CAS No.: 4808-48-4
• Molecular Formula: C16H10 O3
• Molecular Weight: 250.254
• Hs Code.: 2917399090
• European Community (EC) Number: 225-370-2
• NSC Number: 47959
• UNII: 8GSR26474U
• DSSTox Substance ID: DTXSID10197410
• Nikkaji Number: J262.467B
• Wikidata: Q83070287
• ChEMBL ID: CHEMBL2270557
• Mol file: 4808-48-4.mol

Synonyms:diphenylmaleic anhydride

Chemical Property of Diphenylmaleic anhydride

Chemical Property:

• Vapor Pressure: 7.67E-08mmHg at 25°C
• Melting Point: 159-162 °C(lit.)
• Boiling Point: 236°C 15mm
• Flash Point: 215.4°C
• PSA: 43.37000
• Density: 1.314g/cm³
• LogP: 2.68080
• Sensitive.: Moisture Sensitive
• Solubility.: DMF: soluble
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 250.062994177
• Heavy Atom Count: 19
• Complexity: 372

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3-Diphenylmaleic Anhydride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=C(C(=O)OC2=O)C3=CC=CC=C3

Technology Process of Diphenylmaleic anhydride

There total 120 articles about Diphenylmaleic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C24H18N2O3 → 2,3-diphenylmaleic anhydride (4808-48-4) + acetic acid-(4-amino-anilide); hydrochloride (43036-07-3)

Guidance literature:

C₂₄H₁₈N₂O₃; With potassium hydroxide; In ethanol; water; at 80 ℃; for 2h; Green chemistry;

With hydrogenchloride; In ethanol; water; pH=4; Green chemistry;

DOI:10.1039/c6gc01318j

Reference yield: 95.0%

C25H20N2O3 → 2,3-diphenylmaleic anhydride (4808-48-4) + N-benzylglycinamide hydrochloride (20432-97-7)

Guidance literature:

C₂₅H₂₀N₂O₃; With potassium carbonate; In ethanol; water; at 60 ℃; for 2h; Green chemistry;

With hydrogenchloride; In ethanol; water; pH=4; Green chemistry;

DOI:10.1039/c6gc01318j

Reference yield: 94.0%

1-(4-bromobenzyl)-3,4-diphenyl-1H-pyrrole-2,5-dione → 2,3-diphenylmaleic anhydride (4808-48-4) + 4-bromobenzylamine hydrochloride (26177-44-6)

Guidance literature:

1-(4-bromobenzyl)-3,4-diphenyl-1H-pyrrole-2,5-dione; With potassium hydroxide; In ethanol; water; at 102 ℃; for 0.133333h; Microwave irradiation; Green chemistry;

With hydrogenchloride; In ethanol; water; pH=4; Temperature; Green chemistry;

DOI:10.1039/c6gc01318j

upstream raw materials:

benzenediazonium

(Z)-2-phenylbut-2-enedioic acid

3,4-diphenylcyclopent-3-enone

meso-2,3-diphenylsuccinic acid

Downstream raw materials:

5-benzylidene-3,4-diphenyl-5H-furan-2-one

(Z)-2,3-diphenylbut-2-enedioic acid diethyl ester

3,4-diphenyl-1-(p-tolyl)-1H-pyrrole-2,5-dione

1,3,4-triphenyl-2,5-dihydro-1H-2,5-azoledione

Refernces

• 1、 Bao, Xiaodong,Cui, Sunliang,Jin, Jian,Zeng, Linwei. "Facile Synthesis of γ-Butenolides and Maleic Anhydrides via Annulation of α-Keto Acids and Triazenyl Alkynes". . . Retrieved 2022/02/14.
• 2、 Mei, Xiaofei,Wang, Jingwei,Zhou, Zhonggao,Wu, Shiyi,Huang, Limei,Lin, Zhenghuan,Ling, Qidan. "Diarylmaleic anhydrides: unusual organic luminescence, multi-stimuli response and photochromism". . p. 2135 - 2141. Retrieved 2017/03/09.