N,N-Diethylmethylamine

Base Information

• Chemical Name: N,N-Diethylmethylamine
• CAS No.: 616-39-7
• Molecular Formula: C5H13N
• Molecular Weight: 87.1649
• Hs Code.: 29211990
• European Community (EC) Number: 210-480-5
• UNII: 2Y6BJW3KUD
• DSSTox Substance ID: DTXSID8060664
• Nikkaji Number: J79.744H
• Wikipedia: N,N-diethylmethylamine
• Wikidata: Q23993534
• ChEMBL ID: CHEMBL2448813
• Mol file: 616-39-7.mol

Synonyms:diethylmethylamine;diethylmethylamine hydrochloride;N-ethyl-N-methyl-ethylamine;N-methyl-diethylamine

Chemical Property of N,N-Diethylmethylamine

Chemical Property:

• Appearance/Colour: clear colorless to pale yellow liquid
• Vapor Pressure: 169mmHg at 25°C
• Melting Point: -196 °C
• Refractive Index: n20/D 1.389(lit.)
• Boiling Point: 92.1 °C at 760 mmHg
• PKA: 10.35(at 25℃)
• Flash Point: 2.2 °C
• PSA: 3.24000
• Density: 0.757 g/cm³
• LogP: 0.95800
• Storage Temp.: Flammables area
• Water Solubility.: 310.5g/L(49.40 oC)
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 87.104799419
• Heavy Atom Count: 6
• Complexity: 23.1

Purity/Quality:

N,N-Diethylmethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C
• Hazard Codes: F,C
• Statements: 11-20/22-34
• Safety Statements: 16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCN(C)CC
• Uses: Desalination of brackish water, chemical inter-mediate, acid neutralizer. N,N-Diethylmethylamine is used in preparation method of black phosphorus nanosheet covalently grafted with Dialkylmethylamine.

Technology Process of N,N-Diethylmethylamine

There total 49 articles about N,N-Diethylmethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(1H-indol-3-yl)dimethylsulfonium perchlorate + diethylamine (109-89-7) → 3-methylthioindole (40015-10-9) + N,N-diethylnmethylamine (616-39-7)

Guidance literature:

at 55 ℃; for 1h;

DOI:10.1248/cpb.c12-00882

Reference yield: 97.0%

triethylsilane (617-86-7) + bis-(diethylamino)methane (102-53-4) → N,N-diethylnmethylamine (616-39-7) + (diethylamino)triethylsilane (6022-10-2)

Guidance literature:

With nickel; at 140 - 150 ℃;

Reference yield: 93.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + diethylamine (109-89-7) → N,N-diethylnmethylamine (616-39-7)

Guidance literature:

at 120 ℃; for 8h; under 10801.1 Torr;

upstream raw materials:

methyl magnesium iodide

diethyl ether

N-methyl N,N-bis(butoxymethyl)amine

N-formyldiethylamine

Downstream raw materials:

formaldehyd

N-Ethylmethylamine

acetaldehyde

diethylamine

Refernces

• 1、 Guo, Chenjun,Zhang, Fangcao,Yu, Chong,Luo, Yunjie. "Reduction of Amides to Amines with Pinacolborane Catalyzed by Heterogeneous Lanthanum Catalyst La(CH2C6H4NMe2- o)3@SBA-15". supporting information. p. 13122 - 13135. Retrieved 2021/08/31.
• 2、 Rooney, Conor L.,Wu, Yueshen,Tao, Zixu,Wang, Hailiang. "Electrochemical Reductive N-Methylation with CO2Enabled by a Molecular Catalyst". supporting information. p. 19983 - 19991. Retrieved 2021/12/01.