N-Phenylbenzohydroxamic acid

Base Information

• Chemical Name: N-Phenylbenzohydroxamic acid
• CAS No.: 304-88-1
• Molecular Formula: C13H11NO2
• Molecular Weight: 213.236
• Hs Code.: 29280000
• European Community (EC) Number: 206-158-9
• NSC Number: 42454
• UNII: SV2RRM5KQ8
• DSSTox Substance ID: DTXSID6059788
• Nikkaji Number: J151.264A
• Wikidata: Q72501337
• Mol file: 304-88-1.mol

Synonyms:BPHA;N-Benzoyl-N-phenylhydroxamic acid;N-Benzoyl-N-phenylhydroxylamine;N-Hydroxy-N-phenylbenzamide;N-Hydroxybenzanilide;NSC 42454;

Chemical Property of N-Phenylbenzohydroxamic acid

Chemical Property:

• Appearance/Colour: off-white fibrous powder
• Vapor Pressure: 4.19E-06mmHg at 25°C
• Melting Point: 118-120 °C(lit.)
• Refractive Index: 1.666
• Boiling Point: 369.2 °C at 760 mmHg
• PKA: 8.09±0.19(Predicted)
• Flash Point: 177.1 °C
• PSA: 40.54000
• Density: 1.27 g/cm³
• LogP: 2.72260
• Storage Temp.: 2-8°C
• Water Solubility.: Practically insoluble in water
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 213.078978594
• Heavy Atom Count: 16
• Complexity: 230

Purity/Quality:

98% ^*data from raw suppliers

N-Hydroxybenzanilide ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Aromatics (Nitrogen)
• Canonical SMILES: C1=CC=C(C=C1)C(=O)N(C2=CC=CC=C2)O
• Uses: N-Benzoyl-N-phenylhydroxylamine was used as a complexing agent for studying the dispersive liquid-liquid microextraction based on solidification of floating organic drop (DLLME-SFO) behavior of vanadium (V). It was used as an extractant in the determination of beryllium in natural waters.

Technology Process of N-Phenylbenzohydroxamic acid

There total 25 articles about N-Phenylbenzohydroxamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

benzoyl chloride (98-88-4) + phenylhydroxylamine oxalate (84447-15-4) → N-phenylbenzohydroxamic acid (304-88-1)

Guidance literature:

With sodium hydrogencarbonate; In water; benzene; for 0.666667h;

Reference yield: 94.0%

benzaldehyde (100-52-7) + Nitrosobenzene (586-96-9) → N-phenylbenzohydroxamic acid (304-88-1)

Guidance literature:

With 3-(N-morpholino)propanesulfonic acid; benzaldehyde lyase; thiamine diphosphate; magnesium sulfate; In dichloromethane; at 30 ℃; for 96h; pH=7; buffer; Enzymatic reaction;

DOI:10.1002/adsc.201000735

Reference yield: 91.0%

N-phenyl-N-benzoyl-O-methylhydroxylamine (54245-99-7) → N-phenylbenzohydroxamic acid (304-88-1)

Guidance literature:

With aluminium trichloride; dimethylsulfide; for 0.25h; Ambient temperature;

upstream raw materials:

N-benzoyl-N-phenyl-O-(benzoyl)hydroxylamine

benzaldehyde

nitrobenzene

benzoyl chloride

Downstream raw materials:

N-phenyl-N-benzoyl-O-methylhydroxylamine

N-Diphenylacetoxy-N-phenyl-benzamide

dibenzoyl disulfide

1-thiobenzoyloxy-2-(N-benzoylamino)benzene

Refernces

• 1、 Nakamura, Itaru,Owada, Mao,Jo, Takeru,Terada, Masahiro. "Concerted [1,3]-Rearrangement in Cationic Cobalt-Catalyzed Reaction of O-(Alkoxycarbonyl)-N-arylhydroxylamines". supporting information. p. 2194 - 2196. Retrieved 2017/04/27.
• 2、 Song, Xiaoxiao,Ni, Qijian,Grossmann, Andre,Enders, Dieter. "N-heterocyclic-carbene-catalyzed one-pot synthesis of hydroxamic esters". supporting information. p. 2965 - 2969. Retrieved 2014/01/06.