10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate

Base Information

• Chemical Name: 10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate
• CAS No.: 1286209-75-3
• Molecular Formula: C₂₂H₃₆O₅
• Molecular Weight: 380.525
• Mol file: 1286209-75-3.mol

Synonyms:10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate

Chemical Property of 10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate

There total 6 articles about 10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,10-Decanediol (112-47-0) → 10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate (1286209-75-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrabutylammomium bromide; hydrogen bromide / water / 0.08 h / 100 °C / Microwave irradiation

2.1: potassium tert-butylate / tetrahydrofuran; toluene / 0.5 h / 0 °C

3.1: palladium diacetate; triethylamine; triphenylphosphine / 72 h / 120 °C / Inert atmosphere

3.2: 3 h / 25 °C

4.1: iodine / 1 h / 25 °C

With potassium tert-butylate; tetrabutylammomium bromide; hydrogen bromide; iodine; palladium diacetate; triethylamine; triphenylphosphine; In tetrahydrofuran; water; toluene; 3.1: Heck reaction;

DOI:10.1021/op200051v

Reference yield:

1-bromo-10-decanol (53463-68-6) → 10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate (1286209-75-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium tert-butylate / tetrahydrofuran; toluene / 0.5 h / 0 °C

2.1: palladium diacetate; triethylamine; triphenylphosphine / 72 h / 120 °C / Inert atmosphere

2.2: 3 h / 25 °C

3.1: iodine / 1 h / 25 °C

With potassium tert-butylate; iodine; palladium diacetate; triethylamine; triphenylphosphine; In tetrahydrofuran; toluene; 2.1: Heck reaction;

DOI:10.1021/op200051v

Reference yield:

3,4,5-trimethoxytoluene (6443-69-2) → 10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate (1286209-75-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: nitric acid; potassium bromide / acetic anhydride / 1.25 h / 20 °C

2.1: palladium diacetate; triethylamine; triphenylphosphine / 72 h / 120 °C / Inert atmosphere

2.2: 3 h / 25 °C

3.1: iodine / 1 h / 25 °C

With iodine; nitric acid; palladium diacetate; triethylamine; triphenylphosphine; potassium bromide; In acetic anhydride; 2.1: Heck reaction;

DOI:10.1021/op200051v

upstream raw materials:

10-(2,3,4-trimethoxy-6-methylphenyl)decan-1-ol

acetic anhydride

1,10-Decanediol

1-bromo-10-decanol

Downstream raw materials:

2,3-dimethoxy-5-methyl-6-(10'-acetoxydecyl)-1,4-benzoquinone

Refernces