Technology Process of 10-(2,3,4-trimethoxy-6-methylphenyl)decan-1-ol
There total 4 articles about 10-(2,3,4-trimethoxy-6-methylphenyl)decan-1-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
9-Decen-1-ol; 2-bromo-3,4,5-trimethoxy-1-methylbenzene;
With
palladium diacetate; triethylamine; triphenylphosphine;
at 120 ℃;
for 72h;
Inert atmosphere;
With
palladium 10% on activated carbon; hydrogen;
In
ethanol;
at 25 ℃;
for 3h;
DOI:10.1021/op200051v
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetrabutylammomium bromide; hydrogen bromide / water / 0.08 h / 100 °C / Microwave irradiation
2.1: potassium tert-butylate / tetrahydrofuran; toluene / 0.5 h / 0 °C
3.1: palladium diacetate; triethylamine; triphenylphosphine / 72 h / 120 °C / Inert atmosphere
3.2: 3 h / 25 °C
With
potassium tert-butylate; tetrabutylammomium bromide; hydrogen bromide; palladium diacetate; triethylamine; triphenylphosphine;
In
tetrahydrofuran; water; toluene;
3.1: Heck reaction;
DOI:10.1021/op200051v
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium tert-butylate / tetrahydrofuran; toluene / 0.5 h / 0 °C
2.1: palladium diacetate; triethylamine; triphenylphosphine / 72 h / 120 °C / Inert atmosphere
2.2: 3 h / 25 °C
With
potassium tert-butylate; palladium diacetate; triethylamine; triphenylphosphine;
In
tetrahydrofuran; toluene;
2.1: Heck reaction;
DOI:10.1021/op200051v
