6'''-N-CbzAHB paromomycin

Base Information

• Chemical Name: 6'''-N-CbzAHB paromomycin
• CAS No.: 1312471-08-1
• Molecular Formula: C₃₅H₅₈N₆O₁₈
• Molecular Weight: 850.875
• Mol file: 1312471-08-1.mol

Synonyms:6'''-N-CbzAHB paromomycin

Chemical Property of 6'''-N-CbzAHB paromomycin

Chemical Property:

Purity/Quality:

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Technology Process of 6'''-N-CbzAHB paromomycin

There total 1 articles about 6'''-N-CbzAHB paromomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

paromomycin sulfate (7205-49-4) + N-[(S)-4-benzyloxycarbonylamino-2-hydroxy-butyryloxy]succinimide (40371-52-6) → 6'''-N-CbzAHB paromomycin (1312471-08-1)

Guidance literature:

With potassium carbonate; In water; acetonitrile; at 20 ℃; for 16h;

DOI:10.1039/c0ob01133a

Reference yield: 92.0%

6'''-N-CbzAHB paromomycin (1312471-08-1) → 6'''-N-AHB paromomycin (1312471-09-2)

Guidance literature:

With 5% Pd(II)/C(eggshell); hydrogen; In methanol; water; at 20 ℃; for 2h;

DOI:10.1039/c0ob01133a

upstream raw materials:

paromomycin sulfate

N-[(S)-4-benzyloxycarbonylamino-2-hydroxy-butyryloxy]succinimide

Downstream raw materials:

6'''-N-AHB paromomycin

Refernces