N,N-dimethyl-4-(2-(pyridine-4-yl)ethyl)aniline

Base Information

• Chemical Name: N,N-dimethyl-4-(2-(pyridine-4-yl)ethyl)aniline
• CAS No.: 86590-65-0
• Molecular Formula: C₁₅H₁₈N₂
• Molecular Weight: 226.321
• Mol file: 86590-65-0.mol

Synonyms:N,N-dimethyl-4-(2-(pyridine-4-yl)ethyl)aniline

Chemical Property of N,N-dimethyl-4-(2-(pyridine-4-yl)ethyl)aniline

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N,N-dimethyl-4-(2-(pyridine-4-yl)ethyl)aniline

There total 4 articles about N,N-dimethyl-4-(2-(pyridine-4-yl)ethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N,N-dimethyl-4-[(pyrydin-4-yl)ethenyl]aniline → N,N-dimethyl-4-(2-(pyridine-4-yl)ethyl)aniline (86590-65-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In formic acid; at 60 ℃; for 2h;

DOI:10.1002/chem.200802373

Reference yield: 88.0%

picoline (108-89-4) + N,N-dimethyl-4-hydroxymethylaniline (1703-46-4) → N,N-dimethyl-4-(2-(pyridine-4-yl)ethyl)aniline (86590-65-0)

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; 18-crown-6 ether; potassium tert-butylate; In tetrahydrofuran; at 120 ℃; for 20h; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.0c02635

Reference yield: 30.0%

1-Adamantyl bromide (768-90-1) + (E)-4-[4-(dimethylamino)styryl]pyridine (889-36-1,68971-00-6,68971-01-7) → N,N-dimethyl-4-(2-(pyridine-4-yl)ethyl)aniline (86590-65-0) + 1-(Adamant-1-yl)-2-(4-dimethylaminophenyl)-1-(pyrid-4-yl)-ethan (86590-63-8) + 1-(Adamant-1-yl)-1-(4-dimethylaminophenyl)-2-(pyrid-4-yl)-ethan (86590-64-9)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; electrolysis, Hg/Ag/0.1 M AgI, E = -1.65 V;

upstream raw materials:

1-Adamantyl bromide

(E)-4-[4-(dimethylamino)styryl]pyridine

picoline

N,N-dimethyl-4-hydroxymethylaniline

Refernces

• 1、 Cleland, Deidre M.,Irwin, Garth,Wagner, Pawel,Officer, David L.,Gordon, Keith C.. "Linker conjugation effects in rhenium(I) bifunctional hole-transport/ emitter molecules". experimental part. p. 3682 - 3690. Retrieved 2009/12/24.