Cefsulodin

Base Information Edit

Chemical Name:Cefsulodin
CAS No.:62587-73-9
Molecular Formula:C22H20 N4 O8 S2
Molecular Weight:532.555
Hs Code.:
UNII:OV42LHE42B
DSSTox Substance ID:DTXSID6022769
Wikipedia:Cefsulodin
NCI Thesaurus Code:C98227
Pharos Ligand ID:GVMY5JC926WK
Metabolomics Workbench ID:53050
ChEMBL ID:CHEMBL3351077
Mol file:62587-73-9.mol

Synonyms:Abbott 46811;Cefsulodin;Cefsulodin Monosodium Salt;Cefsulodin Sodium;CGP 7174 E;CGP-7174-E;CGP7174E;Monaspor;Monosodium Salt, Cefsulodin;Pyocefal;SCE 129;SCE-129;SCE129;Sodium, Cefsulodin

Suppliers and Price of Cefsulodin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Cefsulodin
1g
$ 230.00

AHH
Cefsulodin 98%
5g
$ 350.00

Total 25 raw suppliers

Chemical Property of Cefsulodin Edit

Chemical Property:

PSA：227.39000
LogP:-0.12670
Storage Temp.:0-5°C
XLogP3:0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:7
Exact Mass:532.07225596
Heavy Atom Count:36
Complexity:1050

Purity/Quality:

99% ^*data from raw suppliers

Cefsulodin ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)S(=O)(=O)O)C(=O)[O-])C[N+]4=CC=C(C=C4)C(=O)N
Isomeric SMILES:C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)S(=O)(=O)O)C(=O)[O-])C[N+]4=CC=C(C=C4)C(=O)N
Description Cefsulodin is a semi-synthetic, third-generation cephalosporin antibiotic with a narrow spectrum of activity. It was first synthesized and patented by the Takeda Pharmaceutical Company in 1977. Cefsulodin has activity against Pseudomonas aeruginosa and Staphylococcus aureus but little activity against other bacteria. It is eliminated renally and has a serum half-life similar to ceftazidime and cefoperazone. Cefsulodin appears to be well tolerated and relatively free of any significant toxicity except for nausea and vomiting, which appear to be related to the infusion rate.
Uses Cefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. Cefuslodin is used in CIN (cefsulodin-Irgasan-novobiocin) agar to select for microorganisms such as E. coli. Cefsulodin is a substrate for rat Oatp1a4. It has been used to study multidrug resistance-associated protein 4 in efflux transport of prostaglandin E2 across the mouse blood-brain barrier. Cefsulodin is used to study the effect of expression, binding, and inhibition of PBP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Therapeutic Function Antibiotic

Technology Process of Cefsulodin

There total 19 articles about Cefsulodin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: