Phenylarsine oxide

Base Information

• Chemical Name: Phenylarsine oxide
• CAS No.: 637-03-6
• Deprecated CAS: 8052-79-7
• Molecular Formula: C6H5 As O
• Molecular Weight: 168.027
• Hs Code.: 29310099
• European Community (EC) Number: 211-275-3
• NSC Number: 42470
• UNII: 0HUR2WY345
• DSSTox Substance ID: DTXSID5042249
• Nikkaji Number: J6.913B
• Wikipedia: Phenylarsine_oxide
• Wikidata: Q20128250
• ChEMBL ID: CHEMBL477683
• Mol file: 637-03-6.mol

Synonyms:oxophenylarsine;phenylarsenoxide;phenylarsine oxide

Chemical Property of Phenylarsine oxide

Chemical Property:

• Appearance/Colour: WHITE TO ALMOST WHITE CRYSTALS OR CRYST. POWDER
• Melting Point: 145-148 °C
• Boiling Point: 100oC
• PSA: 17.07000
• Density: 1
• LogP: 0.47410
• Storage Temp.: Poison room
• Solubility.: DMSO: 50 mg/mL
• Water Solubility.: Soluble in dimethyl sulfoxide, chloroform, benzene, ether, ethanol, 50:50 dimethyl sulfoxide:1 M hydrochloric acid (3.0 mg/ml) a
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 167.955634
• Heavy Atom Count: 8
• Complexity: 76.6

Purity/Quality:

98%,99%, ^*data from raw suppliers

Phenylarsine Oxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): TN
• Hazard Codes: T,N
• Statements: 23/25-50/53
• Safety Statements: 20/21-28-45-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Arsenic Compounds, Organic
• Canonical SMILES: C1=CC=C(C=C1)[As]=O
• Uses: Phenylarsine oxide is used as a poultry coccidiostat in veterinary medicine. It is also used in a membrane-permeable protein tyrosine phosphatase inhibitor.

Technology Process of Phenylarsine oxide

There total 31 articles about Phenylarsine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphenylmercury(II) (587-85-9,1337-09-3) → phenylarsine oxide (637-03-6)

Guidance literature:

With arsenic trichloride; at 130 - 140 ℃; beim Eintragen des entstandenen Phenyldichlorarsins in warme verduennte Natronlauge;

Reference yield:

phenylarsonic acid (98-05-5) → phenylarsine oxide (637-03-6)

Guidance literature:

With sulfuric acid; sulfur dioxide; hydrogen iodide;

Reference yield:

phenylmagnesium bromide → phenylarsine oxide (637-03-6)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: AsCl₃ / 130 - 140 °C / beim Eintragen des entstandenen Phenyldichlorarsins in warme verduennte Natronlauge

With diethyl ether; arsenic trichloride;

upstream raw materials:

diethyl ether

dichlorophenylarsine

methylammonium carbonate

phenylarsonic acid

Downstream raw materials:

diphenylarsinic acid

chlorodiphenylarsine

phenylarsonous acid-(thiocarbonic acid O-ethyl ester)-thioanhydride

bis(benzoylthio)phenylarsine

Refernces