Technology Process of 1-cyclopropylcyclohexylamine
There total 3 articles about 1-cyclopropylcyclohexylamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
diethyl ether;
1.) 12 h, 2.) reflux, 1 h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 91 percent / NaN3, CF3COOH / CHCl3 / 4 h
2: LAH / diethyl ether / 1.) 12 h, 2.) reflux, 1 h
With
lithium aluminium tetrahydride; sodium azide; trifluoroacetic acid;
In
diethyl ether; chloroform;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) t-BuLi / 1.) ether, pentane, -78 deg C, 1 h, 2.) a) -78 deg C, 4 h, b) from -78 deg C to RT, 3 h
2: 91 percent / NaN3, CF3COOH / CHCl3 / 4 h
3: LAH / diethyl ether / 1.) 12 h, 2.) reflux, 1 h
With
lithium aluminium tetrahydride; sodium azide; tert.-butyl lithium; trifluoroacetic acid;
In
diethyl ether; chloroform;
