5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE

Base Information

• Chemical Name: 5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE
• CAS No.: 97-55-2
• Molecular Formula: C₅H₁₃O₁₄P₃
• Molecular Weight: 390.071
• Mol file: 97-55-2.mol

Synonyms:Ribofuranose,5-(dihydrogen phosphate) 1-(trihydrogen pyrophosphate) (8CI)

Chemical Property of 5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE

Chemical Property:

• Vapor Pressure: 6.14E-30mmHg at 25°C
• Boiling Point: 804.4°Cat760mmHg
• Flash Point: 440.3°C
• PSA: 259.17000
• Density: 2.15g/cm³
• LogP: -2.23130

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE

There total 3 articles about 5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

orotidine 5'-monophosphate (2149-82-8) → orotic acid (65-86-1,58915-47-2,6784-70-9) + 5-phosphoribosyl-1-pyrophosphate (97-55-2,7540-64-9,99945-37-6,130384-52-0)

Guidance literature:

With Salmonella typhimurium OMP synthase wild type; magnesium chloride; at 30 ℃; pH=8; Reagent/catalyst; Kinetics; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1021/bi300082s

Reference yield:

benzyl-(O2,O3-carbonyl-O5-diphenoxyphosphoryl-β-D-ribofuranoside) (122174-79-2) → 5-phosphoribosyl-1-pyrophosphate (97-55-2,7540-64-9,99945-37-6,130384-52-0)

Guidance literature:

With hydrogen bromide; acetic anhydride; acetic acid; Reagens 4: Benzol; Hydrieren des Reaktionsprodukts an Palladium/Kohle in Methanol und an Platin in Methanol und Behandeln mit Lithiumhydroxid in Wasser;

DOI:10.1021/ja01541a056

Reference yield:

benzyl-β-D-ribofuranoside (54946-48-4) → 5-phosphoribosyl-1-pyrophosphate (97-55-2,7540-64-9,99945-37-6,130384-52-0)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / Behandeln einer Loesung des Reaktionsprodukts in Pyridin mit Phosgen in Toluol

2: hydrogen bromide; acetic acid; acetic acid anhydride / Reagens 4: Benzol; Hydrieren des Reaktionsprodukts an Palladium/Kohle in Methanol und an Platin in Methanol und Behandeln mit Lithiumhydroxid in Wasser

With pyridine; hydrogen bromide; acetic anhydride; acetic acid;

DOI:10.1021/ja01541a056

upstream raw materials:

benzyl-(O²,O³-carbonyl-O⁵-diphenoxyphosphoryl-β-D-ribofuranoside)

benzyl-β-D-ribofuranoside

orotidine 5'-monophosphate

Downstream raw materials:

nicotinamide mononucleotide

5'-Uridylic Acid

6-thioinosine 5'-monophosphate

Guanosine 5'-monophosphate

Refernces