Juvidex

Base Information Edit

Chemical Name:Juvidex
CAS No.:3672-15-9
Deprecated CAS:3311-11-3,7683-50-3,136309-77-8,642477-31-4
Molecular Formula:C₆H₁₃O₉P
Molecular Weight:260.138
Hs Code.:2919900090
UNII:U2S53JF879
DSSTox Substance ID:DTXSID80957947
Nikkaji Number:J425.349C
Wikidata:Q105285555
Metabolomics Workbench ID:56885
Mol file:3672-15-9.mol

Synonyms:Juvidex;6-O-phosphono-D-mannose;aldehydo-D-mannose 6-phosphate;U2S53JF879;aldehydo-D-mannose 6-(dihydrogen phosphate);(2R,3R,4S,5S)-2,3,4,5-Tetrahydroxy-6-oxohexyl dihydrogen phosphate;[(2R,3R,4S,5S)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxyphosphonic acid;UNII-U2S53JF879;SCHEMBL54511;D-MANNOSE, 6-PHOSPHATE;CHEBI:48042;DTXSID80957947;DB11848;A074F4FA-F19B-4AFA-AF19-0E6F967A7E91;((2R,3S,4S,5S)-3,4,5,6-TETRAHYDROXYTETRAHYDRO-2H-PYRAN-2-YL)METHYL DIHYDROGEN PHOSPHATE

Suppliers and Price of Juvidex

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Juvidex Edit

Chemical Property:

Vapor Pressure:4.47E-15mmHg at 25°C
Boiling Point:564.1°Cat760mmHg
PKA:1.84±0.10(Predicted)
Flash Point:295°C
PSA：166.72000
Density:1.97g/cm³
LogP:-3.10440
XLogP3:-4.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:7
Exact Mass:260.02971899
Heavy Atom Count:16
Complexity:263

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(C(C(C(C(C=O)O)O)O)O)OP(=O)(O)O
Isomeric SMILES:C([C@H]([C@H]([C@@H]([C@@H](C=O)O)O)O)O)OP(=O)(O)O
Recent ClinicalTrials:Investigation Into the Safety and Scar-improvement Efficacy of Intradermal Juvidex Dosed Once or Three Times
Recent EU Clinical Trials:A double blind, placebo controlled trial to investigate the efficacy and safety of two concentrations of Juvidex in accelerating the healing of split thickness skin graft donor sites using different dosing regimes

Technology Process of Juvidex

There total 21 articles about Juvidex which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 50-99-7
D-glucose

: 138-08-9
phosphoenolpyruvic acid

: 56-73-5,3672-15-9,6665-00-5,82259-50-5,89396-13-4,92418-43-4,136376-93-7,136376-97-1,136377-00-9,136377-02-1,136377-04-3,136377-07-6,136377-08-7,136377-11-2,136377-13-4,136377-14-5,136457-25-5
D-glucose 6-phosphate

: 57-60-3
piruvate

Guidance literature:: With ammonium sulfate; NAD; pyruvate kinase e; hexokinase; In hexane; water; for 32h; membran-enclosed enzymatic catalysis;
DOI:10.1021/ja00238a067

Reference yield:

: 643-13-0,4300-29-2,6814-87-5,6934-25-4,52050-07-4,67424-99-1,73544-42-0,136598-62-4,136598-64-6,136598-65-7,136598-66-8
D-fructose-6-phosphate

: 56-73-5,3672-15-9,6665-00-5,82259-50-5,89396-13-4,92418-43-4,136376-93-7,136376-97-1,136377-00-9,136377-02-1,136377-04-3,136377-07-6,136377-08-7,136377-11-2,136377-13-4,136377-14-5,136457-25-5
D-glucose 6-phosphate

Guidance literature:: phosphpoglucoisomerase; Rate constant; with 0.1 M sodium arsenate;
DOI:10.1021/jo00262a021

Reference yield:

: 50-99-7
D-glucose

: 56-73-5,3672-15-9,6665-00-5,82259-50-5,89396-13-4,92418-43-4,136376-93-7,136376-97-1,136377-00-9,136377-02-1,136377-04-3,136377-07-6,136377-08-7,136377-11-2,136377-13-4,136377-14-5,136457-25-5
D-glucose 6-phosphate

Guidance literature:: With phosphoric acid; water; toluene; Isolierung aus dem bei der Vergaerung mit Hefe in Loesung vom pH 7 erhaltenen Reaktionsgemisch;