Technology Process of 2-(4-benzyloxybenzyl)-1,3-dithian
There total 2 articles about 2-(4-benzyloxybenzyl)-1,3-dithian which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 3.1 g / thionyl chloride / diethyl ether / 2 h / Heating
2: 4.2 g / n-butyl-lithium / hexane; tetrahydrofuran / 1.) -23 deg C, 1.5 h, 2.) 0 deg C, 14 h
With
n-butyllithium; thionyl chloride;
In
tetrahydrofuran; diethyl ether; hexane;
- Guidance literature:
-
With
n-butyllithium;
In
tetrahydrofuran; hexane;
1.) -23 deg C, 1.5 h, 2.) 0 deg C, 14 h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 3.6 g / mercuric oxide, mercuric chloride / acetonitrile / 6 h / Heating
2: 1.) Raney nickel, 2.) hydrogen / 2.) palladium on charcoal / 1.) ethanol, reflux, 15 - 20 min, 2.) methanol,
3: 2.5 g / triethylamine / CH2Cl2 / 0.17 h / 0 - 10 °C
4: 1.12 g / aq. hydrochloric acid / tetrahydrofuran / 0.67 h / 18 °C
5: 1.83 g / sodium borohydride / methanol / 0.17 h / Ambient temperature
6: sodium hydroxide / methanol; H2O / 1 h / 70 °C
With
hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; hydrogen; nickel; triethylamine; mercury dichloride; mercury(II) oxide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane; water; acetonitrile;
