4,4'-(pyridin-2-ylmethylene)dianiline

Base Information

• Chemical Name: 4,4'-(pyridin-2-ylmethylene)dianiline
• CAS No.: 85171-91-1
• Molecular Formula: C₁₈H₁₇N₃
• Molecular Weight: 275.353
• Mol file: 85171-91-1.mol

Synonyms:4,4'-(pyridin-2-ylmethylene)dianiline

Chemical Property of 4,4'-(pyridin-2-ylmethylene)dianiline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-(pyridin-2-ylmethylene)dianiline

There total 2 articles about 4,4'-(pyridin-2-ylmethylene)dianiline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

pyridine-2-carbaldehyde (1121-60-4) + aniline (62-53-3) → 4,4'-(pyridin-2-ylmethylene)dianiline (85171-91-1)

Guidance literature:

With 3-methyl-1-(4-sulfobutyl)imidazol-3-ium bis((trifluoromethyl)sulfonyl)azanide; In neat (no solvent); at 80 ℃; for 3h;

DOI:10.1039/d1ra03724b

Reference yield: 22.0%

pyridine-2-carbaldehyde (1121-60-4) + aniline hydrochloride (142-04-1,36663-09-9) + aniline (62-53-3) → 4,4'-(pyridin-2-ylmethylene)dianiline (85171-91-1)

Guidance literature:

for 24h; Heating;

DOI:10.1021/jacs.6b03444

Reference yield:

4,4'-(pyridin-2-ylmethylene)dianiline (85171-91-1) → bisacodyl (603-50-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid; sodium nitrite

2: sodium acetate

With sulfuric acid; sodium acetate; sodium nitrite;

upstream raw materials:

pyridine-2-carbaldehyde

aniline

aniline hydrochloride

Downstream raw materials:

4,4'-(2-pyridylmethylene)diphenol

bisacodyl

Refernces

• 1、 Jaratjaroonphong, Jaray,Saeeng, Rungnapha,Senapak, Warapong,Sirion, Uthaiwan,ponpao, nipaphorn. "Metal- And solvent-free synthesis of aniline- And phenol-based triarylmethanes: Via Br?nsted acidic ionic liquid catalyzed Friedel-Crafts reaction". . p. 22692 - 22709. Retrieved 2021/07/21.