5-amino-2-nitrophenol

Base Information

• Chemical Name: 5-amino-2-nitrophenol
• CAS No.: 16292-86-7
• Molecular Formula: C6H6 N2 O3
• Molecular Weight: 154.125
• Mol file: 16292-86-7.mol

Synonyms:2-Nitro-5-aminophenol;3-Hydroxy-4-nitroaniline; 5-Amino-2-nitrophenol

Chemical Property of 5-amino-2-nitrophenol

Chemical Property:

• Vapor Pressure: 2.16E-05mmHg at 25°C
• Boiling Point: 350.5°C at 760 mmHg
• Flash Point: 165.8°C
• Density: 1.511g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-amino-2-nitrophenol

There total 13 articles about 5-amino-2-nitrophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

2,5-dinitrophenol (329-71-5) → 2-hydroxy-4-amino-1-nitrobenzene (16292-86-7) + 5-Nitro-2-aminophenol (121-88-0)

Guidance literature:

With 1-methylcyclohex-1-ene; palladium on activated charcoal; In methanol; at 80 ℃; for 0.166667h; microwave irradiation;

DOI:10.1055/s-2006-939062

Reference yield: 22.0%

3-chloro-4-nitroaniline (825-41-2) → 2-hydroxy-4-amino-1-nitrobenzene (16292-86-7) + 3-chloro-4-nitrophenol (491-11-2) + 4-nitroresorcinol (3163-07-3)

Guidance literature:

With water; sodium hydroxide; at 100 ℃; for 50h;

DOI:10.1021/jo2007219

Reference yield:

7-chloro-6-nitro-4(3H)-quinazolinone (53449-14-2) → 2-hydroxy-4-amino-1-nitrobenzene (16292-86-7) + 2,4-diaminonitrobenzene (5131-58-8) + 2,4-diamino-5-nitro-benzoic acid (81946-23-8)

Guidance literature:

With ammonium hydroxide; In butan-1-ol; at 175 ℃; for 24h;

upstream raw materials:

N,N'-(4-nitro-m-phenylene)-bis-acetamide

5-acetylamino-2-nitro-benzenesulfonic acid

3-Butyl-7-chloro-6-nitro-3H-quinazolin-4-one

7-chloro-6-nitro-4(3H)-quinazolinone

Downstream raw materials:

benzamide, N-[3-[[6-(acetyloxy)hexyl]oxy]-4-nitrophenyl]-4-fluoro-

benzamide,4-fluoro-N-(3-hydroxy-4-nitrophenyl)-

Refernces

• 1、 Jeong, Euigyung,Freeman, Harold S.,Claxton, Larry D.. "Synthesis and characterization of selected 4,4′-diaminoalkoxyazobenzenes". experimental part. p. 100 - 108. Retrieved 2010/12/18.
• 2、 Kumar, Shiv,Kansal, V. K.,Bhaduri, A. P.. "Possible Anthelmintic Agents: Syntheses of Various Imidazoquinazolinone Carbamates". . p. 1068 - 1071. Retrieved 2007/10/02.