1,1'-DIHYDROXYBICYCLOHEXYL

Base Information

• Chemical Name: 1,1'-DIHYDROXYBICYCLOHEXYL
• CAS No.: 2888-11-1
• Molecular Formula: C12H22 O2
• Molecular Weight: 198.305
• Mol file: 2888-11-1.mol

Synonyms:[Bicyclohexyl]-1,1'-diol(6CI,7CI,8CI); 1,1'-Bicyclohexane-1,1'-diol; 1,1'-Dicyclohexanol;1,1'-Dihydroxy-1,1'-bicyclohexyl; 1,1'-Dihydroxy-1,1'-dicyclohexyl;Bis[cyclohexane]-1,1'-diol; Cyclohexanone pinacol; Dicyclohexyl-1,1'-diol; NSC1472

Chemical Property of 1,1'-DIHYDROXYBICYCLOHEXYL

Chemical Property:

• Melting Point: 126-127oC
• Boiling Point: 304.3oC at 760 mmHg
• Flash Point: 139.4oC
• PSA: 40.46000
• Density: 1.117g/cm3
• LogP: 2.37680

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,1'-DIHYDROXYBICYCLOHEXYL

There total 22 articles about 1,1'-DIHYDROXYBICYCLOHEXYL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.5%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → 1,1'-bicyclohexane-1,1'-diol (2888-11-1) + cyclohexanol (108-93-0)

Guidance literature:

With water; titanium tetrachloride; zinc; In diethyl ether; at 40 ℃; for 15h; Solvent; Inert atmosphere;

DOI:10.1039/c7cc05101h

Reference yield: 77.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + allyl bromide (106-95-6) → 1-allyl-1-cyclohexanol (1123-34-8) + 1,1'-bicyclohexane-1,1'-diol (2888-11-1)

Guidance literature:

allyl bromide; With samarium; iodine; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

cyclohexanone; With water; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2017.01.091

Reference yield: 71.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + 1-chloro-3,3,4,4,5-pentamethyl-2-oxa-3-silahexane (125816-34-4) → 1,1'-bicyclohexane-1,1'-diol (2888-11-1) + 1-dimethylthexylsilyloxymethylcyclohexanol (144314-48-7)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; for 10h; Ambient temperature;

upstream raw materials:

cyclohexanone

Tetrahydro-4H-pyran-4-one

dichloromethane

Methyl 3-bromopropionate

Refernces

• 1、 Li, Jianyong,Niu, Qingsheng,Li, Shanchan,Sun, Yuehao,Zhou, Qian,Lv, Xin,Wang, Xiaoxia. "MeOH or H2O as efficient additive to switch the reactivity of allylSmBr towards carbonyl compounds". supporting information. p. 1250 - 1253. Retrieved 2017/03/10.
• 2、 Banik, Bimal K.,Banik, Indrani,Samajdar, Susanta,Cuellar, Rogelio. "Samarium/N-bromosuccinimide-induced reductive dimerization of carbonyl compounds". . p. 2319 - 2322. Retrieved 2007/10/03.