p-Amino-N,alpha-dimethylphenethylamine

Base Information

• Chemical Name: p-Amino-N,alpha-dimethylphenethylamine
• CAS No.: 4302-87-8
• Molecular Formula: C10H16N2
• Molecular Weight: 164.28
• NSC Number: 27584
• UNII: S70CN675K0
• DSSTox Substance ID: DTXSID10874118
• Nikkaji Number: J13.695F,J71.114D
• Wikidata: Q27288751
• Mol file: 4302-87-8.mol

Synonyms:p-Amino-N,alpha-dimethylphenethylamine;S-15;Aniline, p-(2'-methylamino)propyl-;1-(p-Aminophenyl)-2-methylaminopropane;4302-87-8;Phenethylamine, p-amino-N,alpha-dimethyl-;1-(p-Aminophenyl)-2-methylaminopropan;S70CN675K0;NSC-27584;p-Amino-N,.alpha.-dimethylphenethylamine;S 15 (VAN);NSC 27584;UNII-S70CN675K0;alpha-(4-Aminophenyl)-beta-methylamino-propane;1-(p-Aminophenyl)-2-methylaminopropan [German];S 15;d-1-(p-Aminophenyl)-2-methylaminopropane;Aniline, p-(2'-methylamino)propyl-, (+)-;Benzeneethanamine, 4-amino-N,alpha-dimethyl-;Phenethylamine, p-amino-N,.alpha.-dimethyl-;Benzeneethanamine, 4-amino-N,.alpha.-dimethyl-;Phenethylamine, p-amino-N,alpha-dimethyl-, (+)-;WLN: ZR D1Y1&M1;d-1-(p-Aminophenyl)-2-methylamino-propan [German];NIOSH/SG9500100;SCHEMBL10076421;Phenethylamine,.alpha.-dimethyl-;DTXSID10874118;CCAQCUJAADGTGQ-UHFFFAOYSA-N;Benzeneethanamine,.alpha.-dimethyl-;NSC27584;1-(p-Aminophenyl)-2-methylamino-propan;d-1-(p-Aminophenyl)-2-methylamino-propan;dl-1-(p-Aminophenyl)-2-methylaminopropane;P-AMINOPHENETHYL AMINE,N,B-DIMETHYL;(+-)-p-Amino-N,alpha-dimethylphenethylamine;SG95001000;.alpha.-(4-aminophenyl)-.beta.-methylaminopropane;4-AMINO-N,.ALPHA.-DIMETHYLBENZENEETHANAMINE;Phenethylamine, p-amino-N,alpha-dimethyl-, (+-)-;Q27288751;(+/-)-N-methyl-2-(4-amino-phenyl)-1-methyl-ethyl amine;S-15, (+/-)-

Chemical Property of p-Amino-N,alpha-dimethylphenethylamine

Chemical Property:

• Vapor Pressure: 0.00356mmHg at 25°C
• Refractive Index: 1.6210 (estimate)
• Boiling Point: 281.5°C at 760 mmHg
• Flash Point: 143.8°C
• PSA: 38.05000
• Density: 0.985g/cm³
• LogP: 2.39130
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 164.131348519
• Heavy Atom Count: 12
• Complexity: 117

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(CC1=CC=C(C=C1)N)NC

Technology Process of p-Amino-N,alpha-dimethylphenethylamine

There total 5 articles about p-Amino-N,alpha-dimethylphenethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-nitromethamphetamine (4302-88-9) → p-aminomethamphetamine (4302-87-8,64090-81-9)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1016/S0024-3205(99)00629-3

Reference yield:

1-(4-nitrophenyl)propan-2-one (5332-96-7) → p-aminomethamphetamine (4302-87-8,64090-81-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium cyanoborohydride

2: lithium aluminium hydride

With lithium aluminium tetrahydride; sodium cyanoborohydride;

DOI:10.1016/S0024-3205(99)00629-3

Reference yield:

→ p-aminomethamphetamine (4302-87-8,64090-81-9)

Guidance literature:

With hydrogenchloride; ethanol; platinum; Hydrogenation;

upstream raw materials:

N-Methylformamide

formic acid

(4-amino-phenyl)-acetone; hydrochloride

p-nitromethamphetamine

Refernces