(Z)-β-monocyclohomofarnesylic acid dimethyl amide

Base Information

• Chemical Name: (Z)-β-monocyclohomofarnesylic acid dimethyl amide
• CAS No.: 173323-70-1
• Molecular Formula: C₁₈H₃₁NO
• Molecular Weight: 277.45
• Mol file: 173323-70-1.mol

Synonyms:(Z)-β-monocyclohomofarnesylic acid dimethyl amide

Chemical Property of (Z)-β-monocyclohomofarnesylic acid dimethyl amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-β-monocyclohomofarnesylic acid dimethyl amide

There total 3 articles about (Z)-β-monocyclohomofarnesylic acid dimethyl amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.1%

3-methyl-5-(2',6',6'-trimethylcyclohex-1'-enyl)-1-penten-3-ol (99733-97-8) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → (Z)-β-monocyclohomofarnesylic acid dimethyl amide (173323-70-1) + (E)-β-monocyclohomofarnesylic acid dimethyl amide (173323-69-8)

Guidance literature:

In xylene; for 13h; Heating;

DOI:10.1021/jo951908o

Reference yield:

4-(2,6,6-Trimethyl-cyclohex-1-enyl)-butan-2-on (17283-81-7) → (Z)-β-monocyclohomofarnesylic acid dimethyl amide (173323-70-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 96.3 percent / tetrahydrofuran / 1.) 10 deg C, 20 min, 2.) room temperature, 30 min

2: 30.9 percent / xylene / 13 h / Heating

In tetrahydrofuran; xylene;

DOI:10.1021/jo951908o

Reference yield:

→ (Z)-β-monocyclohomofarnesylic acid dimethyl amide (173323-70-1) + (E)-β-monocyclohomofarnesylic acid dimethyl amide (173323-69-8)

Guidance literature:

upstream raw materials:

3-methyl-5-(2',6',6'-trimethylcyclohex-1'-enyl)-1-penten-3-ol

N,N-dimethyl-formamide dimethyl acetal

4-(2,6,6-Trimethyl-cyclohex-1-enyl)-butan-2-on

Downstream raw materials:

(3aRS,5aSR,9aSR,9bSR)-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan

(±)-ambrox

(3aRS,5aRS,9aRS,9bSR)-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan

(Z)-4-Methyl-6-(2',6',6'-trimethyl-1'-cyclohexenyl)hex-3-en-1-ol

Refernces

• 1、 -. "PROCESS FOR PRODUCTION OF (±)-3a,6,6,9a TETRAMETHYLDECAHYDRONAPHTHO[2,1-b]FURAN-2(1H)-ONE". Page/Page column 10. . Retrieved 2009/05/29.