DL-trans-4-Chlorostilbeneoxide

Base Information

• Chemical Name: DL-trans-4-Chlorostilbeneoxide
• CAS No.: 28291-10-3
• Molecular Formula: C14H11 Cl O
• Molecular Weight: 230.694
• Hs Code.: 2910900090
• Nikkaji Number: J232.136J
• Mol file: 28291-10-3.mol

Synonyms:28291-10-3;DL-TRANS-4-CHLOROSTILBENEOXIDE;dl-trans-4-Chlorostilbene oxide;AWZJRRBGXZWVOY-KBPBESRZSA-N;2-(4-Chlorophenyl)-3-phenyloxirane #;trans-2-phenyl-3-(4-chlorophenyl)oxirane;2-(4-Chlorophenyl)-3-phenyloxirane trans-;Oxirane, 2-(4-chlorophenyl)-3-phenyl-, trans-

Chemical Property of DL-trans-4-Chlorostilbeneoxide

Chemical Property:

• Vapor Pressure: 0.000264mmHg at 25°C
• Boiling Point: 333.4°Cat760mmHg
• Flash Point: 156°C
• PSA: 12.53000
• Density: 1.249g/cm³
• LogP: 4.15260
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 230.0498427
• Heavy Atom Count: 16
• Complexity: 229

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2C(O2)C3=CC=C(C=C3)Cl
• Isomeric SMILES: C1=CC=C(C=C1)[C@H]2[C@@H](O2)C3=CC=C(C=C3)Cl

Technology Process of DL-trans-4-Chlorostilbeneoxide

There total 61 articles about DL-trans-4-Chlorostilbeneoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzaldehyde (100-52-7) + C14H12ClN2O2S(1-)*Na(1+) → trans-2-(4-chlorobenzenyl)-3-phenyl-oxirane (28291-10-3)

Guidance literature:

With thiophene; dirhodium tetraacetate; N-benzyl-N,N,N-triethylammonium chloride; In acetonitrile; at 40 ℃; for 3h;

DOI:10.1002/1521-3773(20010417)40:8<1430::AID-ANIE1430>3.0.CO;2-W

Reference yield: 95.0%

benzaldehyde (100-52-7) + p-chlorobenzaldehyde tosylhydrazone sodium salt → trans-2-(4-chlorobenzenyl)-3-phenyl-oxirane (28291-10-3)

Guidance literature:

With thiophene; dirhodium tetraacetate; N-benzyl-N,N,N-triethylammonium chloride; In acetonitrile; at 40 ℃;

DOI:10.1021/ja034606+

Reference yield: 94.0%

phenyldiazomethane (908094-04-2) + 4-chlorobenzaldehyde (104-88-1) → trans-2-(4-chlorobenzenyl)-3-phenyl-oxirane (28291-10-3)

Guidance literature:

With copper acetylacetonate; ethyl isopropyl sulfide; In dichloromethane;

upstream raw materials:

(E)-1-(4-chlorophenyl)-2-phenylethene

phenyldiazomethane

4-chlorobenzaldehyde

sodium 2-benzylidene-1-tosylhydrazin-1-ide

Downstream raw materials:

1-(4-chlorophenyl)-2-phenylethanol

2-(4'-chlorophenyl)-1-phenylethan-1-ol

3-(2-benzothiazolyl)-1,3-diphenyl-2-(4-chlorophenyl)-1-propanol

2-(4-Chloro-phenyl)-2-[2-(4-nitro-phenyl)-ethylamino]-1-phenyl-ethanol

Refernces

• 1、 -. "Method used for direct synthesis of epoxy compounds from alcohol". Paragraph 0140-0147. . Retrieved 2019/10/08.
• 2、 Tiddens, Martine R.,Klein Gebbink, Robertus J. M.,Otte, Matthias. "The B(C6F5)3-Catalyzed Tandem Meinwald Rearrangement-Reductive Amination". supporting information. p. 3714 - 3717. Retrieved 2016/08/16.