sodium 2-benzylidene-1-tosylhydrazin-1-ide

Base Information

• Chemical Name: sodium 2-benzylidene-1-tosylhydrazin-1-ide
• CAS No.: 27992-27-4
• Molecular Formula: C₁₄H₁₃N₂O₂S*Na
• Molecular Weight: 296.325
• Mol file: 27992-27-4.mol

Synonyms:

Chemical Property of sodium 2-benzylidene-1-tosylhydrazin-1-ide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of sodium 2-benzylidene-1-tosylhydrazin-1-ide

There total 3 articles about sodium 2-benzylidene-1-tosylhydrazin-1-ide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

benzaldehyde p-toluenesulfonylhydrazone (1666-17-7) → sodium 2-benzylidene-1-tosylhydrazin-1-ide (27992-27-4,40154-38-9)

Guidance literature:

With sodium hydride; In diethyl ether; for 24h; Ambient temperature;

DOI:10.1002/(SICI)1099-1395(199704)10:4<207::AID-POC883>3.0.CO;2-8

Reference yield:

benzaldehyde (100-52-7) + toluene-4-sulfonic acid hydrazide (1576-35-8) → sodium 2-benzylidene-1-tosylhydrazin-1-ide (27992-27-4,40154-38-9)

Guidance literature:

benzaldehyde; toluene-4-sulfonic acid hydrazide; In 1,4-dioxane; at 20 ℃; for 0.5h;

With sodium hydride; at 20 ℃; for 1h;

DOI:10.1002/1521-3773(20010417)40:8<1430::AID-ANIE1430>3.0.CO;2-W

Reference yield:

benzaldehyde (100-52-7) → sodium 2-benzylidene-1-tosylhydrazin-1-ide (27992-27-4,40154-38-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / ethanol / 5 h / Heating

2: 80 percent / NaH (60percent in mineral oil) / diethyl ether / 24 h / Ambient temperature

With sodium hydride; In diethyl ether; ethanol;

DOI:10.1002/(SICI)1099-1395(199704)10:4<207::AID-POC883>3.0.CO;2-8

upstream raw materials:

benzaldehyde p-toluenesulfonylhydrazone

benzaldehyde

toluene-4-sulfonic acid hydrazide

Downstream raw materials:

2-phenyl-1-p-tolyl-ethanone

phenyl-1 epoxy-1,2 hexane

phenyl(2-methyl-3-phenylcyclopropyl)methanone

(R,R)-trans-stilbene epoxide

Refernces

• 1、 Chirila, Andrei,van Vliet, Kaj M.,Paul, Nanda D.,de Bruin, Bas. "[Co(MeTAA)] Metalloradical Catalytic Route to Ketenes via Carbonylation of Carbene Radicals". supporting information. p. 2251 - 2258. Retrieved 2018/04/09.
• 2、 Aggarwal, Varinder K.,Alonso, Emma,Hynd, George,Lydon, Kevin M.,Palmer, Matthew J.,Porcelloni, Marina,Studley, John R.. "Catalytic asymmetric synthesis of epoxides from aldehydes using sulfur ylides with in situ generation of diazocompounds". . p. 1430 - 1433. Retrieved 2007/10/03.